Back in April of 09 after I was diagnosed the endo started me on metformin. I gradually worked up to my current amount of 2 – 500 milligram pills twice a day. Then about a month after that the endo put me on actose and told me that both of these medications would help with insulin resistence. He told me that weight loss and exercise would also greatly reduce IR. Fast forward to the present day. I’ve lost all the weight I need to. Went off the actose. Yet, the doctor kept me on the metformin. Will metformin contribute much in IR for someone who lost the extra weight and is also a low carber? I guess I’m just wondering what role 2,000 milligrams of metformin a day is actually doing for me? Can I still have a lot of IR left? I’m taking the same dose as I was when I was 75 lbs. heavier. Truthfully I’d like to drop down some on the metformin but should I? Is there something else that metformin does for a diabetic besides helping overcome IR?