Drug Binding Reveals New Hepatitis C Treatment Model

Upon finding that Isis-11 binds to a spot on the Hepatitis C virus needed for viral replication, researchers may have discovered a new structure for future Hepatitis C treatments.

Potential new target for treating Hepatitis C found

ANI, Mar 30, 2010

A team of researchers has discovered that binding of a potent inhibitor of the hepatitis C virus (HCV) to the genetic material of the virus causes a major conformational change that may adversely affect the ability of the virus to replicate.

This discovery, published in the March 29 early edition of the Proceedings of the National Academy of Sciences, provides a potential new target for structure-based design of new hepatitis C treatments.

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