Cytogenetic Studies in Malignancy Cancer

I think I never mention about the relationship between cytogenetics and cancer research in this blog. Cytogenetic studies are proven that can assist to define the diagnosis and deliver clear prognostic differences in cancer. There are many cytogenetic studies of malignancy have been gone through and most of them are related to hematologic disorders. However, those studies constitute only small percentage of all cancer malignancies.

Clinical Value of Cytogenetic Studies in Malignancy Cancer

cytogenetics cancer Cytogenetic Studies in Malignancy Cancer

Recently, there has been a significant progress in knowledge of the recurrent abnormalities in many of solid tumors as well as hematologic malignancies. Consequently, the clinical value of cytogenetic studies in cancer malignancy has been appreciated after the cytogenetic studies of some solid tumors moving out of cancer research environment.

Apart from this, there would be little clinical value in doing cytogenetic studies in cancer malignancy if all the patients with a particular cancer died. The researchers only manage to probe the origins of cancer for those patients. However, after researching in all tumors type by using cytogenetic technique, the presence or absence of many of the genetic abnormalities found has been related to different responses to treatment. Since that, the genetic and cytogenetic studies start to be recognized as important and one of the best choices of treatment for a cancer patient.

Cytogenetic Studies Helps Diagnostic Investigation in Malignancy Cancer

Consequently, cytogenetic analysis of cancer malignancy is considered to provide rapid, accurate and specific results to aid the clinical professionals. This can help to choose the most appropriate type of treatment to the cancer patient in shorter time. However, John Swansbury stated that the diagnosis of a malignancy can be traumatic, and an accurate and early indication of every patient’s prognosis is valuable.

In conclusion, a cytogenetic study remains an essential part of diagnostic investigations of every patient with hematologic malignancy and certain solid tumors without denying the valuable contributions made by other genetic assays.

Reference: Methods in Molecular Biology, vol. 220: Cancer Cytogenetics: Methods and Protocols. Edited by: John Swansbury © Humana Press Inc., Totowa, NJ