Protective Immunity in Special Populations–As part of its biodefense research program, NIAID is issuing a BAA to encourage research to understand the immune status of special populations. This research program seeks to identify the factors and mechanisms that contribute to susceptibility to infection from or limit vaccine efficacy against potential bioterrorism agents and emerging/re-emerging infectious diseases in immunocompromised populations, including neonates, children under 5 years of age, pregnant women, the elderly, and individuals receiving immunosuppressive drug therapies to treat a defective immune response or to suppress the rejection of transplanted organs. Research is needed to understand the mechanisms of immune compromise, and to provide the foundation for the development of novel interventions. This solicitation is a recompetition of the Immune Function and Biodefense in Children, Elderly and Immunocompromised Populations program, with a focus on the mechanisms of immunosuppression. The NIAID anticipates that one or more cost reimbursement completion-type awards will be made beginning on or about March 1, 2011 utilizing special contracting methods, FAR Subpart 17.1 – Multi-year Contracting. The NIAID estimates that the average annual total cost (direct and indirect costs combined) will be $1.5 million per contract. This BAA will be available electronically on/about January 29, 2010.
Posted Date: January 15, 2010
Solicitation Number: BAA-NIAID-DAIT-NIHAI2010085