When leptin and insulin are disrupted with a diet of sugar and grain there is a miscommunication in the body about where to store excess fat.
Some fat will be stored in the abdomen and liver, which throws the liver function off-kilter and starts a process of breakdown of muscle and bone—causing weakness and osteoporosis. Now we have a serious problem of insulin resistance and high blood pressure, heart disease and cancer.
When we see the big apple-shaped middle we are looking at insulin resistance and disease.