DoD Solicitations – April 2010

dodDevelopment of Quantum Computing Technology – The U.S. Army Research Office (ARO) together with the National Security Agency (NSA) solicits proposals for basic and applied research to advance quantum computing technology. Research areas of particular interest include: (1) Robust solid-state qubits and related technologies – Qubits are the foundation of both memory and processing in quantum information systems. In this area of interest, we seek proposals that address the development of single-and few-qubit solid-state devices; (2) Short-to-medium-range quantum information transfer in solid-state systems – This area of interest seeks innovative approaches to transfer quantum information in solid-state systems, including on-chip transfer, off-chip transfer, or both. Selected proposals will greatly advance the current state-of-the-art in relevant performance metrics for a specific solid-state qubit implementation; and (3) Ideas, methods, and procedures for the verification/validation of quantum computing components – A challenge for quantum information processing systems, especially as they increase in size, is the efficient and accurate verification/validation of their performance for the task at hand. In this third area of interest innovative proposals are sought to address the verification/validation of quantum information processor components..  White papers are strongly encouraged but are not required.  Award Ceiling: $3M; Award Floor: $200K.  Eligibility: All.  White Paper Due Date: May 24, 2010. Proposals Due Date: July 12, 2010.

Posted Date: April 27, 2010

Funding Opportunity Number: W911NF-10-R-0007

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Instrumentation Program for Tribal Colleges and Universities (TCUs) – The program aims to enhance science, mathematics, and/or engineering education programs and/or research capabilities through the acquisition of equipment and/or instrumentation that will augment existing facilities, enhance curricula, or develop new laboratories, programs and capabilities in these areas. This includes basic equipment for laboratory and classroom use as well as sophisticated instruments and computers (including software) for advanced studies and research important to the DoD.  Total Funding: $4.8M; Award Ceiling: $400K.  Eligibility: This competition is open only to institutions identified under 10 U.S.C. 2362 (e)(2) on the U.S. Department of Education Postsecondary list for Indian Tribally Controlled Colleges and Universities.  Proposal Due Date: June 15, 2010.

Posted Date: April 24, 2010

Broad Agency Announcement Number: W911NF-10-R-0005

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Computational Toxicology: Biologically-Based Multi-Scale Modeling – The EPA, as part of its Science to Achieve Results (STAR) program, is seeking applications for research in developing quantitative, dose-response models to elucidate the associations between environmental agents and toxicity pathways across multiple scales of biological organization. Additionally, this solicitation calls for research into ways in which the data underlying these models can be managed and shared for easier access, interpretation and use by the broader community of researchers and risk assessors. There are two distinct Research Areas covered by this solicitation: (1) Model Development and Model Evaluation; and (2) Data Management.  Applications must propose research in one of these research areas to be eligible for funding. These two areas of research shall be conducted concurrently in the following way: the research team funded under the second research area shall collaborate with the research teams funded under the first research area to ensure that the latter conform their modeling data to a shared ontology.  Total Funding: $3M.  Eligibility: Public and Private Nonprofit Institutions/Organizations (including institutions of higher education and hospitals). Closing Date: July 15, 2010.

Posted Date: April 15, 2010

Funding Opportunity Number: EPA-G2010-STAR-C4; EPA-G2010-STAR-C3; EPA-G2010-STAR-C2; EPA-G2010-STAR-C1

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DoD SBIR Program 2010.2 – Small high-technology firms are encouraged to submit proposals to DoD for R&D projects with both military and commercial applications in response to SBIR solicitation 2010.2, which will be publicly released on the DoD SBIR Web Site (http://www.acq.osd.mil/sadbu/sbir) on Apr 21, 2010.  Six DoD components will participate in the 2010.2 solicitation – Department of the Army, Department of the Navy, Defense Advanced Research Projects Agency (DARPA), Defense Microelectronics Agency (DMEA), Defense Threat Reduction Agency (DTRA), and the Office of the Secretary of Defense (OSD). The solicitation lists all the R&D topics under which DoD is seeking proposals, and also contains detailed information on the parameters of the SBIR program and how to submit a proposal. Small firms apply first for a six-month phase I award of $70,000 to $150,000 (unless otherwise specified in the component instructions) to test the scientific, technical, and commercial merit of a particular concept. If phase I proves successful, the firm may be invited to apply for a two-year phase II award of $500,000 to $1,000,000 to further develop the concept.  Eligibility: For Profit Businesses with 500 or fewer employees.  Opening Date: May 19, 2010.  Closing Date: June 23, 2010.

Posted Date: April 15, 2010

Solicitation Number: DoDSBIR2010-2

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DoD Amyotrophic Lateral Sclerosis Therapeutic Idea Award – The Therapeutic Idea Award is designed to promote new ideas that are still in the early stages of development with the potential to yield highly impactful data and new avenues of investigation for novel therapeutics for ALS treatment. This mechanism supports conceptually innovative, high-risk/high-reward research that could ultimately lead to critical discoveries or major advancement in ALS therapeutics. Research projects should include a well-formulated, testable hypothesis based on strong scientific rationale.  Innovation and Impact are the most important aspects of the Therapeutic Idea Award.  Research deemed innovative may introduce a new paradigm, challenge current paradigms, introduce novel concepts or agents, or exhibit other uniquely creative qualities that may lead to potential therapeutics for ALS.  Impact describes research that has high potential to significantly impact development of therapeutics for ALS.  Total Funding: $1.92M.  Eligibility: Independent investigators at all academic levels.  Pre-Application Due Date: May 14, 2010.  Full Application Due Date: August 4, 2010.

Posted Date: April 14, 2010

Funding Opportunity Number: W81XWH-10-ALSRP-TIA

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DoD Amyotrophic Lateral Sclerosis Therapeutic Development Award – The Therapeutic Development Award supports the preclinical assessment of therapeutics for ALS. The proposed studies are expected to be empirical in nature and product-driven, but may have a hypothesis-driven approach, provided the focus is on therapeutics. It is anticipated that the agents and/or data generated from these awards will lead to the advancement of therapeutics for ALS. The Therapeutic Development Award mechanism is designed to support preclinical testing and development of therapeutics for ALS. Proposals must include preliminary data relevant to the phase(s) of the preclinical development process covered by the proposed research. The proposal should include a clear statistical plan of analysis, if appropriate. Applicants must clearly and explicitly articulate what impact the project may have on therapeutic development for ALS.  Total Funding: $4.8M.  Eligibility: Independent investigators at all academic levels.  Pre-Application Due Date: May 14, 2010.  Full Application Due Date: August 4, 2010.

Posted Date: April 14, 2010

Funding Opportunity Number: W81XWH-10-ALSRP-TDA

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DoD Gulf War Illness Consortium Development Award – This effort will be executed through two separate award mechanisms, the Consortium Development Award in FY10 and the Consortium Award in FY11. Proposals for the Consortium Development Award are being requested in this program announcement. The Consortium Development Award is an infrastructure development mechanism that provides support to create a Coordinating Center and establish the necessary collaborations at potential Research Sites for the development of a multi-institutional GWI research effort. Participants in this consortium should be scientists and/or clinicians who have made significant contributions to the field of Gulf War Illness research or who have specific expertise related to the multiple symptoms associated with GWI progression. Infrastructure development includes (but is not limited to) establishing appropriate collaborations, outlining an administrative management plan, developing research management and communication plans, and devising an intellectual property plan.  Total Funding: $640K.  Eligibility: Independent investigators at all academic levels.  Closing Date: August 4, 2010.

Posted Date: April 14, 2010

Funding Opportunity Number: W81XWH-10-GWIRP-CONDEV

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DoD Gulf War Illness Clinical Trial Award – The FY10 GWIRP is offering two award mechanisms to evaluate potential interventions for Gulf War Illness: the Clinical Trial Award (CTA) and the Innovative Treatment Evaluation Award  (ITEA).  The Clinical Trial Award described in this FOA is intended to support larger, more definitive (Phase II-III) clinical trials where preliminary and preclinical evidence indicates the potential for substantial benefit for veterans with GWI.  The CTA supports rapid execution of clinical trials with the potential to have a significant impact on the health and lives of veterans with GWI.  The GWIRP seeks proposals that will contribute to identification of effective interventions for GWI. This will include larger, more definitive clinical trials where preliminary and preclinical evidence indicates the potential for substantial benefit for veterans with GWI. Health outcomes of interest include effects of interventions on: 1) Global health measures; 2) Symptoms complexes; 3) Measurable clinical outcomes, biomarkers; 4) GWI subgroups characterized by symptom or other clinical characteristics.  Total Funding: $2.4M.  Eligibility: Independent investigators at all academic levels.  Closing Date: August 4, 2010.

Posted Date: April 14, 2010

Funding Opportunity Number: W81XWH-10-GWIRP-CTA

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DoD Gulf War Illness Investigator-Initiated Research Award – The IIRA supports research focusing on the complex of symptoms known as Gulf War Illness, improving its definition and diagnosis, characterizing disease symptoms, and better understanding its pathobiology. It is intended to encourage basic or clinical developmental research aimed at identification of objective measures to distinguish ill from healthy veterans (e.g., biomarkers) or elucidate potential treatment targets for GWI. Studies that characterize chronic effects of neurotoxic exposures encountered during the Gulf War (and at comparable dosage) are also acceptable.  Particular areas of interest include research on objective indicators of biological processes, or abnormalities in GWI associated with: 1) Central nervous system structure and function; 2) Central neuroinflammatory processes; 3) Neuroendocrine measures; 4) Autonomic nervous system function; 5) Immune parameters; 6) Indicators of chronic infection; 7) Gastrointestinal complaints/symptoms; 8 ) Genetic, genomic, proteomic, or metabolic characteristics.  The IIRA is designed to promote new ideas in Gulf War Illness research.  Total Funding: $2.88M.  Eligibility: Investigators at all academic levels (or equivalent).  Pre-Application Due Date: May 14, 2010.  Full Application Due Date: August 4, 2010.

Posted Date: April 14, 2010

Funding Opportunity Number: W81XWH-10-GWIRP-IIRA

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DoD Gulf War Illness Innovative Treatment Evaluation Award – The GWIRP Innovative Treatment Evaluation Award (ITEA) mechanism supports the initial evaluation of a treatment or intervention in smaller, early phase or pilot clinical trials (Phase II or I/II), and does not require preliminary data. The GWIRP is also offering a Clinical Trial Award (CTA), which supports proposals evaluating treatments of interventions in larger, more definitive clinical trials (Phase II or III), where preliminary and preclinical evidence indicates the potential for substantial benefit for veterans with GWI.  The intent of the ITEA is to provide support for the systematic evaluation of innovative treatment interventions not previously studied in ill Gulf War veterans, with the aim of improving their health and functional status. The results of preliminary studies funded by this award will support future development of larger efficacy studies of the proposed interventions.  Important aspects of the Innovative Treatment Evaluation Award are: 1) Innovation; 2) Preliminary Data; 3) Study Endpoints; 4) GWI Case Definition; 5) GWI Patient Access; 6) IND Applications; 7) Initiation of Trial.  Total Funding: $1.44M.  Eligibility: Independent investigators at all academic levels (or equivalent).  Pre-Application Due Date: May 14, 2010.  Application Due Date: August 4, 2010.

Posted Date: April 14, 2010

Funding Opportunity Number: W81XWH-10-GWIRP-ITEA