Category: News

The paper reviewed here is ‘Differentiating the Cognitive Profile of Schizophrenia from that of Alzheimer Disease and Depression in Later Life’ by Mulsant and colleagues and freely available here. In the abstract the authors conclude that

‘Patients with LLS (Late Life Schizophrenia) have a different cognitive profile than patients with AD (Alzheimer’s Disease) or DEP (Depression in later life). Particularly, memory impairment in LLS seems to be more pronounced in learning than recall‘

Method

• All cases referred to a memory service for consultation were analysed. I wasn’t absolutely clear if this was done retrospectively or prospectively but from the wording it seemed to be retrospective.
• People referred to the service underwent psychiatric and neurological assessments and DSM-IV criteria were used for the diagnoses
• All people referred to the service underwent the following neuropsychological test battery as routine and these test scores were included in the analysis

1. Animal Fluency
2. Boston Naming Test
3. Clock Drawing Test – Freedman Scale
4. California Verbal Learning Test II – Short Form (CVLT)
5. Dementia Rating Scale-2 (DRS)
6. FAS Letter Fluency (FAS)
7. Luria Alternating Diagrams
8. Mini-Mental Status Examination
9. Trail Making Test A and B
10. Wisconsin Card Sorting Test – 64

• It didn’t look as though a single specific hypothesis was being tested. Instead the demographics and cognitive test results from the different groups – DEP, AD, LLS and control group were being compared.
• In the first phase of the statistical analysis, ANOVA was used.
• When differences between groups were identified using the ANOVA, a Bonferroni correction was made for multiple comparisons
• Cohen’s D was used for differences between the LLS and other groups

Results

• LLS (n=25)
• AD (n=15)
• DEP (n=15)
• NC (n=12)
• I thought Figure 1 was a very useful summary of the data and quite intuitive. The Late onset Schizophrenia group are acting as the reference group. In this diagram, group differences at p<0.001 are highlighted with ***. From looking at differences of this significance I noted the following
• The LLS group were significantly better on a number of memory tasks than the AD group
• The control and DEP groups were significantly better than the LLS group on the FAS, DRM memory, WCST categories, CVLT short and long delay free recall
• I wondered if the latter findings were tapping predominantly into frontal lobe function and the AD group findings into medial temporal lobe function

Discussion

• In the discussion, the authors comment on the hierarchy of memory impairment across groups
• The researchers note that the groups have small sample sizes which would reduce the power of the study
• They note the memory impairment of the LLS group compared to the DES and control groups on a number of memory tasks

I thought this was a neat study, showing how service data can be effectively utilised to examine group differences in cognition. This research approach should be reproducible across other services although the components of the test battery will vary. Even so, examination of group differences including vascular dementia and frontotemporal dementia using different test batteries would be valuable.

Call for Authors: If you are interested in writing an article or series of articles for this blog please write to the e-mail address below. Copyright can be retained. Index: An index of the site can be found here. The page contains links to all of the articles in the blog in chronological order. Twitter: You can follow ‘The Amazing World of Psychiatry’ Twitter by clicking on this link. Podcast: You can listen to this post on Odiogo by clicking on this link (there may be a small delay between publishing of the blog article and the availability of the podcast). It is available for a limited period. TAWOP Channel: You can follow the TAWOP Channel on YouTube by clicking on this link. Responses: If you have any comments, you can leave them below or alternatively e-mail [email protected]. Disclaimer: The comments made here represent the opinions of the author and do not represent the profession or any body/organisation. The comments made here are not meant as a source of medical advice and those seeking medical advice are advised to consult with their own doctor. The author is not responsible for the contents of any external sites that are linked to in this blog.

What it is: A redesign of the C/D comparison-test Terminator, the 3-series.

We’ve received more up-to-date information since this article was published in the magazine. Click here for an updated story.

Keep Reading: 2012 BMW 3-Series – Feature

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Back in November, Denise Kaigler left her seat (qjnet/nintendo-ds/corporate-affairs-vp-denise-kaigler-leaves-nintendo.html) as the corporate affairs VP of Nintendo of America. Citing family reasons as the reason for her depature, she also believed that it wasn’t game over for

By Scott M. Fulton, III, Betanews

Amid news yesterday of a discovery by an independent programmer of what appeared to be another door left open for Web apps to access Facebook users’ personal data, Sen. Chuck Schumer (D – N.Y.) called upon the Federal Trade Commission to take the next step in forming the equivalent of a US “privacy commissioner.”

It was the first step in a one-two punch, as Sen. Schumer later joined three other Democrat senators in penning a letter to Facebook CEO Mark Zuckerberg, calling upon him to make his site’s privacy policy clearer and tighter, in order to give the FTC less to scrutinize.

“I am asking the FTC to use the authority given to it to examine practices in the disclosure of private information from social networking sites and to ensure users have the ability to prohibit the sharing of personal information,” reads the statement from Schumer’s office yesterday. “If the FTC feels it does not have the authority to do so under current regulations, I will support them in obtaining the tools and authority to do just that.”

The press office cited recent Facebook issues only made more prominent after last week’s unveiling of the Open Graph platform, which enables other Web sites to opt into Facebook’s sharing system through the inclusion of codes in their <META> tags and new API function calls. The functionality is being marketed to prospective Facebook partners as instant personalization. As Facebook’s updated privacy policy reveals, users can indeed opt out of other sites’ or applications’ instant personalization…on an app-by-app basis.

That means users of sites where Facebook’s “Like” system has just been deployed, will be instantly personalized…until they explicitly report they’d prefer not to be, thank you very much.

“We appreciate that Facebook is attempting to integrate the functionality of several popular Web sites, and that Facebook has carefully selected its initial partners for its new ‘instant personalization’ feature,” reads the Democrat leaders’ letter to Zuckerberg, reprinted this morning by Politico. “We are concerned, however, that this feature will now allow certain third party partners to have access not only to a user’s publicly available profile information, but also to the user’s friend list and the publicly available information about those friends. As a result of the other changes noted above, this class of information now includes significant and personal data points that should be kept private unless the user chooses to share them. Although we are pleased that Facebook allows users to opt-out of sharing private data, many users are unaware of this option and, moreover, find it complicated and confusing to navigate. Facebook should offer users the ability to opt-in to sharing such information, instead of opting out, and should make the process for doing so more clear and coherent.”

Also signing their name to this morning’s letter were Sens. Michael Bennet (D – Colo.), Mark Begich (D – Ark.), and Al Franken (D – Minn.). The senators closed by saying they look forward to the FTC examining this and the other issues they raised, but would hope Facebook would act in the meantime.
The discovery that some private data may be inadvertently shared by Facebook anyway was made by a Google employee named Ping, who posted to his Web site this Facebook app. Essentially, the app acts as a catalog that reveals every data item that is publicly accessible through Facebook’s API (which Ping identifies as the Graph API, but which has actually been a part of Facebook’s platform since before last week).

On Monday, Ping wrote, “Yesterday, I discovered something strange while playing with Facebook’s new Graph API: The API was showing a list of my events, and it seemed that anyone could get this list. Today, I spent a while checking to make sure I wasn’t crazy. I didn’t opt in for this. I even tried setting all my Privacy Settings for maximum privacy. But Facebook is still exposing the list of events I’ve attended, and maybe your events too.”

Ping accompanied his post with a screenshot of some of Mark Zuckerberg’s personal events, pulled up through his API tool.

Betanews tried using the tool to verify Ping’s claims, especially since he later reported that the tool works for some people and not for others. For us, it did not reveal personal data for accounts where personal data was blocked, for any account we tested. In other words, at least for us, Facebook was doing its job.

Early Tuesday morning, Ping reported back that the tool is no longer revealing anyone’s events. “Thanks to the Facebook folks for improving their stuff!” he wrote. Commenters to Ping’s blog also noted that users’ events that were exposed over the weekend, do not appear to be exposed now.

Either a certain someone read that letter, or he may be getting a very interesting visitor. The Hill‘s Kim Hart reported this morning that Deputy Secretary of Defense William Lynn will convene a special meeting on cybersecurity, at Zuckerberg’s office in Palo Alto.

Copyright Betanews, Inc. 2010

For the past month or so several rumors and leaks about Nokia’s next flagship device have been floating around the web.  Today the Nokia N8 becomes official, equipped with some specs and bold statements that will no doubt leave you (at the very least) curious.  According to the official Nokia Blog, “the Nokia N8 will launch with a new breed of camera that promises to capture photos and video to rival dedicated point and shoot cameras,” a rather audacious claim indeed.  

Here are just a few of the specs that the N8 boasts:

• Symbian ^3 for Nokia
• Screen size: 3.5″
• Capacitive touch screen
• 12 megapixel camera with Carl Zeiss optics
• Orientation sensor (Accelerometer)
• Bluetooth version 2.1 with Enhanced Data Rate
• Integrated GPS, A-GPS receivers
• Internal memory: 16 GB
• MicroSD card slot capacity up to 32 GB (for a total of 48GB!)
• Size: 113.5 x 59 x 12.9 mm
• Weight (with battery): 135 g

As you can see the N8 will be the first device sporting Symbian ^3, though according to MobileCrunch, its not much different than Sybmian ^1 and Symbian ^2.  SlashGear is also reporting (based on a Russian blogger’s review of a pre-release unit) that while the “stills from the camera are good…the 720p HD video isn’t anything special in comparison to other handsets.”  However, in a later piece on the same topic, they make the point that much of the negative press the device is receiving comes from a single review on a prototype unit.  

That being said, all the videos and specs look great, so my suggestion to readers would be to check it out for themselves when it becomes available in Europe in Q3 of this year.  The N8 is expected to sell for €370 and there is no exact release date or carrier information as of yet.  To form your own opinion of the N8, go here to view all sorts of related media.  And don’t forget to stop back and leave your opinion in the comments!

Via SlashGear, MobileCrunch, NokiaConversations

What it is: A small, relatively affordable two-seat sports car available as a coupe or a convertible. Styling will be fully modern.

Keep Reading: 2013 Jaguar XE – Feature

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After a weekend climate rally on the Mall in Washington attended by 150,000 people – including at least two blue Navii people – the 31 major environmental groups in the US today sent a letter to congress demanding that it return to the table on the climate bill before the summer recess, citing the Senate’s “profound responsibility to future generations to enact policies that enhance our economic, environmental and national security”.

The letter was signed by the key representatives of all of the major environmental groups – the Sierra Club, the Natural Resources Defense Council and Environment America. The activist groups signed on; led by 1Sky, Climate Solutions and the Alliance for Climate Protection.

They were joined by the groups that have expertize in the field of climate policy – the Union of Concerned Scientists, Environmental Defense Fund, Center for American Progress Action Fund, Center for International Environmental Law and the Pew Environment Group. (more…)

Time for some reader feedback!  We want to know which Android handset and wireless provider make for the best combination.  Is it the Droid Incredible because of the hardware? Maybe something from T-Mobile because of rate plans?

Leave your opinion in the comments below!

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  We’re pleased to announce another giveaway of Slacker Radio Plus accounts!  If you’re not familiar with the streaming music service and Android application, it allows for personalized radio stations b…

Sometimes a company’s best move may be to hire a consultant, but that help certainly doesn’t come cheaply.

For example, Alcoa, Inc. (AA) just signed an agreement to pay industry veteran Bernt Reitan $125,000 for “Consultant’s expertise and knowledge of aluminum manufacturing and fabrication, smelting, bauxite mining, bauxite refining and/or the sale or distribution of alumina and alumina related products, alumina refining and smelting technology and smelter and refinery construction.”  Until recently, Reitan was the Executive VP and Group President, Global Primary Products at Alcoa; he currently holds the title “Chairman’s Counsel.” He will retire on August 1, 2010, when the consulting agreement takes effect.  Per its terms, Alcoa can’t ask Reitan to work more than 25 days per calendar year, which means he gets a minimum of $5,000 per diem, or $625 per hour if he works an 8-hour day (plus expenses).

But another company is paying its consultant even more. Late last week, Snap-On, Inc. (SNA) filed this Transition Services Agreement as an attachment to its quarterly report.

The agreement involves Martin Ellen, who until recently worked as Snap-On’s Senior Vice President – Finance/CFO. While in that job, in 2009 Ellen received a base salary of $472,500 and total compensation of nearly $2 million. On April 1, 2010, Ellen became the Executive Vice President/CFO at Dr. Pepper Snapple Group, Inc. (DPS), where he will earn quite a bit more. In that job (according to an 8-K the company filed in mid-February), Ellen starts with a base salary of $525,000, a target bonus that ranges between 90-180% of that salary, and an initial equity grant of more than $1.3 million. He’ll also get nonqualified stock options and RSUs with a total cash value of $3.75 million to replace equity awards that Ellen lost when he left Snap-On.

Snap-On wants Ellen’s help as it prepares for arbitration with CIT Group, Inc.  There’s a good summary of the dispute on pp. 27-28 of the Q, but – in a nutshell – the disagreement involves various alleged underpayments made in the context of a financial services joint venture.  Snap-On alleges damages of $115 about million, and CIT Group’s response alleges damages in excess of $110 million.

The agreement requires Ellen to attend meetings and assist the company as it produces documents and generally prepares its case. He is also to assist Snap-On “…with the continued transition of the business of Snap-on Credit LLC as a result of the termination of the Company’s former joint venture arrangements with CIT Group Inc.” and to provide “assistance to the Company in connection with other matters as may be reasonably requested.”

In exchange for his help, Snap-On is paying Ellen:

“…a monthly retainer of $20,000 per month, payable on the last business day of each calendar month during the Term. This retainer shall cover up to 60 hours of Services per calendar quarter, and shall be paid whether or not any Services are requested by the Company. Any hours over 60 in a calendar quarter shall be paid at a rate of $1,000 per hour, and will be paid along with the following month’s retainer payment.”

Thus, the agreement assures Ellen at least $1,000 per hour, assuming he works all 60 hours per calendar quarter. If Snap-On only needs him for half that time (10 hours a month), his hourly rate doubles. And if it doesn’t call him at all one month, Ellen still gets $20,000.

To be sure, an executive like Ellen presumably has a lot of knowledge that will benefit Snap-On as it prepares for arbitration. What is less clear is how a busy executive in a new job will find the time to help his old employer get ready for its arbitration hearing. But regardless, it’s worth another $240,000 to Ellen… maybe even more.

Image source: purpleslog via Flickr

————

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In a bid to increase capacity for the next generation of small-block, fuel efficient engines, GM has announced that they will be investing $893 million in upgrading 5 existing North American engine-related facilities.

According to GM, the move will preserve or create 1,600 jobs. The upgrades are necessary to meet the increasingly stringent fuel economy and emissions standards just enacted by the EPA.

(more…)

Pro Tip: If you mute your speakers, these people look absolutely insane.

Big trouble at Greystar Resources Ltd. is negatively impacting shares in Colombian gold mining neighbour Ventana Gold Inc. this week, but investors probably have nothing to worry about, Daniel Earle, a TD Newcrest analyst says.

On Monday, Greystar announced that it would be subject to changes in Colombia's mining code, that essentially ban mining in Colombia's "Paramo" ecosystem. Greystar's Angostura gold-silver project infringes on that area. 

While Greystar stock has plummeted more 40% on the news, shares in Ventana Gold, whose flagship La Bodega project is adjacent to Angostura, have also been hit, falling more than 5% since last Friday.   

Time will tell whether the sell off in Ventana was warranted, but according to Mr. Earle, the new regulation and environmental request is not applicable to La Bodega based on the much lower elevation of the project.

"We understand that the highest point on the La Bodega concession where the La Bodega zone butts up against the Greystar property boundary is a little under 2,900m," he said in a note to clients, maintaining his Speculative Buy rating and $12 price target.

"Furthermore, we note that the La Bodega property has an approved environmental management plan that provides the company with protection from subsequent environmental legislation.

Mr. Earle said he spoke with Ventana management, who told him they have been aware of this specific issue for some time and believe there is no carry-over impact for La Bodega. 

David Pett

It was a big week for experimental military aircraft, with the Air Force’s secretive X-37B space plane and the Navy’s biofuel-powered “Green Hornet” both achieving successful test flights. But the most ambitious—the HTV-2 hypersonic glider under development by the Defense Advanced Research Projects Agency (DARPA)—lost contact with its operators during its run.

Launched from Vandenberg AFB, Calif. on April 22, the unmanned HTV-2 was planned to cross the Pacific and impact the ocean north of Kwajalein Atoll in the first of two flights to demonstrate technology for a prompt global strike weapon [Aviation Week]. It successfully achieved separation from its booster rocket high in the atmosphere; however, nine minutes into the test the glider lost communication. Now the military is studying the test flight telemetry to figure out where the HTV-2 would have crashed down.

Thursday’s mission was the first of two planned in the HTV-2 program, which uses Minotaur 4 boosters developed by Orbital Sciences Corp. from decommissioned Peacekeeper intercontinental ballistic missiles. The U.S. military is trying to develop technology to respond to threats around the globe at speeds of Mach 20 or greater, according to DARPA [AP]. DARPA is being fairly tight-lipped about possible uses for the HTV-2, but it’s not hard to see why the military would be excited about an aircraft that travels about 13,000 miles per hour and can strike on the other side of the world with “little or no advanced warning,” as the agency says.

Program manager Paul Erbland says the key to HTV-2 flying at such speed and height is its carbon shell, which is capable of withstanding extreme heat and pressure. It doesn’t burn off material to get rid of heat. The vehicle is designed to fly at a low angle of attack relative to other hypersonic vehicles. “Shuttle and similar vehicles fly at roughly 40°; HTV-2 is substantially below that,” he said [Aviation Week]. As for the communications failure, DARPA has some time to address the problem before the craft’s second planned test flight next March.

Related Content:
80beats: Will the Pentagon Build the Jetsons’ Flying Car?
80beats: Highway to the Green Zone? Navy To Test a Supersonic Biofuel Jet
80beats: DARPA Wants a Biofuel Jet, While Germany Works on a Hydrogen Plane
80beats: DARPA’s Kooky $40,000 Scavenger Hunt

Image: DARPA

The LG Optimus formerly know around the web as the LG GT540, will be headed to the UK this May. LG is a late entry into the Android game but they are making a valiant effort to pump out quality Android devices. To bad there isn’t a price tag on this one but expect it to be affordable.

Specifications:

• Geo tag enabled 3-megapixel camera
• 3.5mm headset jack
• Bluetooth 2.1
• Wi-Fi, GPS
• 3-inch HVGA touchscreen
• DivX and Xvid ready

If you’re bored or just have some time on your hands the press release is at the bottom. We’ll be sure to keep you updated on this device as more specs and pricing become available.

” Berkshire, 27 April, 2010 — LG Electronics, (LG), a global leader and technology innovator in mobile communications, today announced the launch of an Android-powered smartphone, LG Optimus (LG GT540), a handset offering an optimal environment for first-time smartphone users with easy and convenient mobile access.

LG Optimus allows users to enjoy diverse Android applications and automatic account synchronisation with all Google mobile services. LG Optimus also features enhanced social networking functions in a high-powered multimedia environment.

“LG Optimus is the ideal choice for early smartphone users who expect all the features of smartphones without the complexity,” said Dr. Skott Ahn, President and CEO of LG Electronics Mobile Communications Company. “This is a device that was designed for regular people who want to jump into the smartphone experience but have been hesitant to do so because of the learning curve. By making LG Optimus more approachable, we hope more people will give smartphones a try.”

Optimal Convenience
LG Optimus delivers smartphone benefits in a convenient Google internet package. With an automatically synchronised Google account, users need to only log-in once to enjoy YouTube, Gmail, Gtalk, Google Maps and more. With easy access to more than 30,000 downloadable applications and games from the Android Market, users can easily customise and expand their LG Optimus experience.

The SN Manager offers integrated access to social networking sites in a convenient platform that can manage multiple accounts. LG’s dedicated Social Networking Client allows users to easily keep track of their Facebook, Twitter and Bebo accounts. Moreover, the Social Networking System (SNS) widgets provide real-time status updates directly to the home screen without having to access any other applications. The handset’s multitasking feature allows users to view updates from friends and access their social media sites while simultaneously searching the phone’s contact list.

The user interface is customisable for maximum convenience. The LG Optimus can be customised to show anywhere from three to seven home screens displaying frequently used applications, news and weather, among other information, depending on user preference. Additionally, the main menu can be personalised to include up to 10 editable categories for faster, easier navigation.

Optimal Excitement
LG Optimus includes high-powered entertainment features that make the phone extra fun to use. The advanced media player allows users to watch DivX and Xvid videos directly without separate encoding and browsing multimedia files is especially enjoyable with the 3D thumbnail gallery.

The phone’s 3MP camera supports geo-tagging, auto face-tagging and face-to-action technology to allow users to create and share multimedia content from the phone. The LG Optimus has a built-in video editor with storyboard function so that users can add music and text to videos directly on the phone.

LG Optimus boasts a distinctive design that is both sleek and soft and is available in black and silver. What’s more, the phone includes a long-lasting 1500mAh battery, a 3.5mm headphone jack, Bluetooth 2.1 capability, assisted GPS, 32GB of expandable microSD memory and four customisable home screen themes together with enhanced idle lock screen notifications.

The LG Optimus will be available in the UK from 1 May. For more information about the LG Optimus visit http://www.lg-optimus.com or for general LG Mobile information visit www.lg.com/uk/mobile.”

The PalmInfocenter Store has rolled out a new mobile accessory store. The mobile optimized store lets users browse and buy Palm accessories right from their Palm device. The store carries many of the latest and most popular accessories for Palm devices including the Pre, Pixi, Centro, Treo’s and classic PDA’s.

PalmInfocenter has long had an accessory store, which compliments our Palm OS software store. The store carries a wide range of accessories including cases, bluetooth headsets, extended batteries, chargers, cables and cradles, memory cards and much more.

With the addition of the mobile accessory shop, customers can now get everything they need to make the most of their device in one convent spot. Shipping is available worldwide and starts at just $5.95 for most items delivered in the US. Payment can be made via major credit cards or paypal. Simply visit the PalmInfocenter mobile site and browse to the store, or key in m.palminfocenter.com on your phone.

Filed under: Budget, Minivan/Van, Auctions, Volkswagen, Celebrities

You can’t sell everything on eBay. Case in point: The auction site has a pretty stiff policy against the selling of what it calls “murderabillia” or anything “closely associated with notorious murders within the last 100 years.” We can debate whether euthanasia qualifies constitutes actual murder, but regardless, Dr. Jack Kevorkian’s 1968 Volkswagen Van evidently falls into that category on eBay, as it was the site of several of the infamous doctor’s reported 130 assisted suicides throughout the years.

As for the van, The Detroit News notes that Kevorkian gave it up to be crushed back in 1997. Somehow, the VW escaped its fate and wound up in the hands of Jack Finn, a retired Volkswagen parts dealer. Finn says the vehicle may run and stop, but it isn’t safe to drive on public roads and is in need of a full restoration.

Since eBay Motors gave Finn’s listing the boot, Kruse Auctions has agreed to sell the vehicle at its May 14-16 event.

Kevorkian was convicted of second degree murder in 1999 and subsequently served eight years in prison. He has recently become the focus of attention once again thanks to the new You Don’t Know Jack movie staring Al Pacino.

[Source: The Detroit News]

Report: eBay Motors labels Kevorkian VW Bus as ‘murderabilia,’ delists auction originally appeared on Autoblog on Tue, 27 Apr 2010 13:01:00 EST. Please see our terms for use of feeds.

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Heather Steingruebl is a BABloggee. She contacted me and told me some chilling news: her daughter Elise was recently diagnosed with leukemia. She’s being treated, and I know we all hope things go well for her.

But in the meantime, this makes Elise susceptible to many preventable diseases. We need people to get vaccinated! As Heather says,

Vaccinate. Elise and thousands of kids like her are counting on not dying from things like measles and whooping cough while they fight cancer. Unless it’s a specific health risk to you or your child, just vaccinate. Please.

She also implores people to get on the bone marrow donation registry. Search around online for information on how to do this. I plan on doing this myself.

My heart goes out to her and her family, as it does to anyone affected by this awful illness. I’m going to find out what booster shots I need, because I take this issue very seriously. I hope you do too.

Volkswagen is using some brains to ensure that the upcoming multi-media platform in VW cars will be a certain success. VW has announced an open innovation contest dubbed the ‘App My Ride’ where it is going to challenge developers to create new software applications for its multi-media platform.

As there are €14,000 in cash and non-cash prizes available, VW can be rest assured of some stunning entries which is definitely going to help the brand in the longer run. This ‘App My Ride’ project draws inspiration from the booming Smartphone industry which is well assisted by amazing applications. What is great is that there is a separate prize for student participants so even the fresh talent is not being ignored by VW. [via devicemag]