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  • When F1 2009 won’t do, try the $191K Cruden Hexatech simulator

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    We give thumbs up to Cruden‘s reason for building a $191,500 F1 simulator: “Snooker rooms, swimming pools, gyms and cinemas have been done.” So there. If you’re over waiting for Codemasters to release F1 2009 on a real platform, or waiting for GT5 to ever show up and you have enough money to buy an SLS AMG and several weeks of track time, the Hexatech is waiting for you.

    The fully-suspended system can be tailored to provide feedback based on the chassis setup, wheelbase and track, tire and suspension settings, drive train (engine, gearbox, differentials), aero loading, aero draft (slip streaming), steering, brakes and driver aids such as traction control, ABS, and more. It even has seat belt tensioners. And it isn’t just for F1: the sim does NASCAR, WRC, and 24-Hour racing, too. Three 42-inch screens, or a projector and a room with at least a 10-foot ceiling will keep you in the action.

    If you want one but you don’t have that kind of dosh, there’s still time to make a wish and be extra nice before Santa makes his final decision. Or you could ask Ferrari if you can borrow theirs

    [Source: F1 Fanatic]

    When F1 2009 won’t do, try the $191K Cruden Hexatech simulator originally appeared on Autoblog on Thu, 24 Dec 2009 11:00:00 EST. Please see our terms for use of feeds.

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  • Would Paul Volcker Make A Better Fed Chair Than Bernanke?

     

    Joe Weisenthal, Deputy Editor, The Business Insider

    Your Questions (4 min)

    • I just inherited 100K, I am 28, no debt, good job, etc. If you could make one big bet on the market with it, what would it be? – heavy hitter
    • Joe, what are you buying right now? – CNBC
    • As ADIA [Abu Dhabi Investment Authority] is trying to exit the Citi deal, do you expect any more sovereign funds to sell stakes in western corporations to have cash to buy distressed assets in the Middle East and Eastern Europe? – Sir Lorenz
    • Do you think Paul Volcker would make a better Fed Chair than Bernanke? – dcortex
    • Do you have any political philosophy or consistent understanding of the world on the basis of which you reason? Your analysis seems to favor the wealthy and I am wondering why. – SS
    • Should Joe get with Jon Stewart and start a business editorial feature on the Daily Show? – Let’s Get Real

    Produced By: Kamelia Angelova & William Wei

    More Video: TBI Calendar Click HERE >

    Join the conversation about this story »

  • Flu about gone… and the family is arriving

    UPDATE: 12-30-09: I’m feeling better. I still have the ear infection, but overall things are much better. I’m going to get back at it today – and that will include a bit of blogging as well as removing a tremendous amount of snow from the driveway and walks around our place. The fresh air should do me good…

    UPDATE 12-28-09: I’m still very ill. Spent Christmas day with an earache. Haven’t been able to hear out of my left ear at all since then. Went to the clinic and got a prescription for some high-powered and spendy antibiotics to kill the ear infection. Hopefully, I’ll be back to blogging soon.

    It’s been a tough week. Unfortunately, I remember most of it. Patty and I had just gotten home from the annual Salt Lake Christmas Tour when I began to feel crummy. The next thing I knew, I felt terrible… and I’ve been down with the flu ever since. Patty got a bad cold during the tour week and is still trying to get rid of that too. So we’ve been quite a pair.

    We’re both on the mend now. Feeling much better, thank you. Today we wrap a few presents and get ready for the kids, grandkids, and friends to arrive for Christmas dinner tomorrow. I’m actually feeling well enough that I do think this may be fun.

    Merry Christmas to all our many friends out there. Have a terrific holiday.

  • Watch: Dragon Quest VI DS Jump Festa 2010 trailer

    Square Enix loves remakes. While the same doesn’t seem to hold true to that game where that psycho pretty boy skewered that flower girl, it does when it comes to Dragon Quest VI. A new trailer for

  • Have a real cigarette – have a Camel (Nov, 1958)

    Have a real cigarette – have a Camel

    New kind of whirlybird! This portable one-man ‘copter can be completely assembled in the field and ready to fly in a hurry. Its pilot, Dick Peck, is a Camel smoker. “I want a cigarette that smokes mild and tastes good,” he says. “Camels do both.”

    So good and mild . . . the finest taste in smoking!

    Millions of smokers like Dick Peck know the difference between “just smoking” and Camels. They know you get more to enjoy out of Camels —so rich in taste, so mild to smoke. No other cigarette has ever equalled this exclusive blend of costly tobaccos. Today, more people smoke Camels than any other cigarette of any kind. How about you?

  • Novexel Offers Exit to Atlas and Abingworth

    Ryan McBride wrote:

    Atlas Venture and Abingworth Management, two venture firms with local offices in Waltham, MA, are in line to exit their investments in French antibiotics developer Novexel, which announced yesterday it would be acquired by London-based drug giant AstraZeneca in a $505 million deal. AstraZeneca has agreed to pay $350 million in cash for all shares in Novexel, provide the firm’s shareholders with up to $75 million in potential milestone payments tied to the success of Novexel’s drugs, and transfer the $80 million in cash Novexel has to the shareholders. It’s not clear how much Atlas and Abingwoth had invested in the privately held antibiotics developer. The acquisition is expected to close in the first quarter of 2010.







  • HOLLYWOOD’S NEW IDEAL FIGURE (Feb, 1937)

    So Hollywood’s new figure is apparently being tan? Besides the fact that tan is not really a “figure” do we really need five pages to explain this?

    HOLLYWOOD’S NEW IDEAL FIGURE

    By Adela Rogers St. Johns

    The Glamour and Charm of Lovely Screen Stars Are Heightened by a New Femininity Born of Sunbathing

    THEY ask that question, “Is Hollywood developing a new ideal figure?” I say yes. A great big yes. New curves with all the glamour of the exotic boudoir, the sex appeal we used to talk about, plus the verve and honesty and beauty of strength and a figure made perfect under the suns and winds and perfumes of the deserts and the high places.

    The great beauties of Hollywood today are created by the forces of nature, and they represent woman at her highest and most alluring charm. Because she has all that health and strength can give a woman. Gone are the emaciated types once thought so desirable.

    Let’s see why and what this new femininity is.

    They come pretty close to being fresh air and sun worshippers, these women who must keep their beauty always at its zenith, their condition always at its peak and their nerves always under control if they are to keep out in front in the battle of Hollywood. To keep their place in the sun, they have to keep out in the sun, if you know what I mean.

    If you see Carole Lombard with her bags piled in her shining sports roadster and holler, “Hi, Carole, where you going?” the chances are a hundred to one she’ll say Palm Springs, which is where the sun is hottest and brightest all winter long.

    There are a lot of sun spots, favorites of the movie stars. There’s La Quinta, with its little rambling bungalows and brilliant flowers right on the desert—La Quinta, where I had my last real visit with Marie Dressier before we lost her. It was her favorite spot then, and she used to say that the sun warmed more than her “old bones,” as she called them. I went down to stay a few days with her and we sat in the sun and she used to say, “There’s more God-given health and strength in a few rays of sunlight than there is in all the medicine ever conceived by man.”

    Then there’s Honolulu, which is becoming more and more popular with screen stars all the time. It isn’t really so very far from California these days, with the fast ocean liners and now Pan American’s wonderful China Clippers that can fly it over night. Janet Gaynor has a house there and she spends every moment that she gets between pictures on the beach at Waikiki.

    Then of course there’s Santa Barbara, a garden spot with miles of white beach, only two hours’ drive away, and Santa Monica and Malibu, which are actually suburbs of Hollywood and where many of the stars have permanent homes the year round. Norma Shearer has a stately mansion at Santa Monica and you can hear the Pacific rolling right up to the front door.

    Arrowhead Hot Springs is a few hours up into the mountains, right on Big Bear Lake. It’s famed for its snow and winter sports, but just as many people go up there from Hollywood in the summer—following the sun.

    BUT Palm Springs, 126 miles from Hollywood along magnificent boulevards, is the chief sun spot, the temple of the sun worshipers, the place where you can’t walk without seeing some motion picture beauty lying in the sun, getting full of health and relaxation. That’s where Ginger Rogers spent her honeymoon with Lew Ayres.

    It’s the most fascinating place you can imagine—a funny, tiny little town of one street, right in the middle of the whitest, hottest desert you ever saw. Behind it, rise many colored rocks, great huge piles of them, colored rust-red, and blue, and turquoise green, with palm trees growing among them. Along the main street are hotels, built in the style of early California, with gleaming white plaster and little balconies and bright desert flowers and purple Bougainvillea trailing over the walls. You eat outdoors under brilliant umbrellas, and there are swimming pools and bicycles and tennis courts and funny cow ponies to ride out through the desert sands—and movie stars. And always the hot, bright sunshine.

    Thinking back, it seems to me that Joan Crawford started the real cult of sun worshiping. At least, she gave me my first lesson. It’s quite a while ago and considerable water has gone under the bridges since, as you will see. Joan was married then to young Douglas Fairbanks and they were spending a day with Douglas Fairbanks, Sr., and Mary Pickford—who were still married to each other.

    I’d gone in for lunch and found the four of them beside the lovely salt water pool at Fairford, which was then Doug and Mary’s Santa Monica beach house. We sat around talking in our bathing suits and then Joan said, “Come on and have a sun-bath.” As I was stretched out on the grass in my bathing suit with the sun beating down on me I said, “I’m having a sun-bath right now. What’s wrong with this?” But Joan had other ideas, so I went along.

    Right on the sand and near the waves was a canvas affair about eight feet high and I imagine about fifteen feet square. Inside there were rubber mattresses, a small table covered with bottles, and that was all. We took off our bathing suits and rubbed ourselves all over with some kind of oil— it was olive oil mixed with cocoanut oil and something else that smelled very nice—and lay down on rubber mattresses.

    The sun was blazing, that clear, dry, golden heat that is typical of California when the sky is blue and cloudless. It seemed to penetrate right through you. Joan’s idea of a sun-bath was to toast yourself nicely on all sides. First we lay on our stomachs and then we lay on our backs and then on each side.

    Joan, who already had an exquisite ivory tan, looked like some nymph escaped from Olympus, the home of the gods and goddesses. She was sheer beauty and health and youth and her hair, in the sunshine, was like an autumn leaf.

    While we toasted she explained to me about sun-bathing.

    “There isn’t anything in the world that relaxes you as sun-baths do,” she said. “When you’ve been working hard on a picture, long hours under the lights, straining and at a tension all the time the picture is being made, you get so nervous and tight that you feel as though you never could relax again.”

    I knew how difficult it was for the high-strung, emotional girl beside me to relax at any time. I knew that the very thing that went over on the screen, that vibrant quality of being alive, kept her strung at a high pitch most of the time.

    “But the sun will always relax me,” she said. “You mustn’t stay too long. It’s your first day. I’ll probably go to sleep anyhow. You’d better put on some clothes. I’ll stay a while longer.”

    As a matter of fact, she did go to sleep before I got into my bathing suit and went out for a dip in the ocean.

    The great Garbo had a sun-bath in ‘ the back yard of her house when she lived in Beverly Hills. It was the same kind—a canvas room without a roof, the canvas strung on iron pipes. I made one myself this year at my home in Great Neck, Long Island. Sheets will do as well as canvas, if you’re sure no one is going to be around much.

    Garbo took a sun-bath every morning, when she was working, and every day when she wasn’t. Even if she managed long walks beside the ocean, and she loves walking beside the sea better than any other form of exercise, she always got her sun-bath. But the thing: she hadn’t realized was that she had an audience—no, two audiences.

    HER adorers had discovered where she lived. The front of that small house in Beverly was blank with a plain wall that gave no indication of what went on inside. But the garden in the back, though it was walled, could be seen from the road which ran above it. And every day crowds of people gathered up on the road and stared at Garbo’s canvas walls. A photographer even took pictures of it and finally airplanes started flying too low—then Garbo gave up and bought a house down near Santa Monica where she could sun-bathe in privacy and peace.

    But when she played tennis at Jack Gilbert’s house on the hill, she always lay in the little sand beach beside the swimming pool for hours afterward, letting the sun pour down upon her, never speaking, sometimes going to sleep.

    The first time I ever saw Arline Judge she was wearing a white bathing suit and a pair of scarlet satin slippers with very high heels. I was sitting in my front yard at Malibu when she walked by and I didn’t know who she was but I thought she had the most beautiful figure I had ever seen in my life. Later, when she became en- gaged to Wesley Ruggles, the director who just made “Valiant Is the Word for Carrie,” I saw a lot of her because Wes had a house next door to mine at Malibu. In case you don’t know, Malibu is a beach colony about eleven miles up the coast from Santa Monica. There are only about a hundred houses there and most of them belong to film folk. There is nothing between your front door and the ocean except a strip of beach. The houses are so close together that if you are neighbors you can shout good-night through the walls. Arline remained my idea of the way. a girl should be built. And when we became friends—I was her bridesmaid when she and Wes were married—I asked her how she kept that exquisite, doll-like figure. Of course she had been a dancer and that usually does it. But I found out, too, that Arline was a fine swimmer, usually got a dip before she dashed to the studio in the morning, and that she was an ardent sun-worshiper. She claims—I don’t know whether this is true or not—that plenty of sun keeps the fat off you. That it sort of burns it off. We rigged up a sun-bath down at Malibu and used to fry for half an hour every day in the sun. Or—of course bathing suits nowadays aren’t really much between you and the sun—we’d walk from one end of the beach to the other when the sun was hottest.

    BOTH Joan and Constance Bennett had houses at Malibu, and Jeanette MacDonald used to spend a lot of time down there visiting Ernst Lubitsch. But Jeanette always had to be careful about the sun because she has one of those very fair, thin skins that burn easily. I remember once when we had adjoining bungalows at the Desert Inn in Palm Springs and Jeanette began her sun-baths—they have dozens of these little canvas things scattered about on the lawn which forms a court inside the rambling rectangle of bungalows—with about thirty seconds the first day, increased it to a minute the second and finally got where she could stay out for ten minutes at a time.

    Of course in Palm Springs you wear so few clothes at any time—except in the evening—that you are practically sun-bathing all the time. The favorite costume for women is sneakers, shorts, and a halter. Or at best a sleeveless, low-necked sports blouse.

    Ginger Rogers isn’t a real dyed-in-the-wool sun-bather. Like Miss Mac-Donald, she has to be very careful about burning. These red-heads! And when she doesn’t burn she freckles. But she spent her honeymoon playing deck tennis on the lawn with Lew Ayres. Other girls may look cute in shorts and one of those handkerchief things tied around their necks, but for my money Ginger looks cutest.

    “I adore sun-baths,” she told me, “but I do have to be careful. It’s funny. I work so hard on a picture—dancing as much as I do makes it even harder work than it is for other people, and making pictures is hard enough any time—that I’m worn out. Getting out in the sun and air is the best thing there is for me. It makes me rest and relax and sleep—why, after you’ve been out in the sun most of the day, the way we are down here, playing tennis and swimming and walking, you sleep twelve hours utterly relaxed and it does you more good than anything on earth. You know, there’s such a thing as air-bathing, too. When I’m afraid to take time to get out in the sun long enough to get a little tan so I can really sun-bathe, I take air-baths instead. They’re the same as sun-baths, only you don’t let the sun shine directly on you.”

    Ruth Chatterton has a perfectly beautiful little desert house at La Quinta, right on the edge of the desert, where she spends weeks when she isn’t working. Ruth isn’t exactly what you’d call an outdoor girl. There is a little bit of the orchid quality about Ruth and she looks more perfect in a shining satin tea gown in her green and white drawing-room than she does in shorts or bathing suit. But she loves the sun and follows it down to La Quinta and spends long, peaceful hours in a deck chair in her garden, restoring her soul with contemplation of the desert which she says always brings her peace, and her body with the sunlight and air.

    Just after Luise Rainer came over from Vienna to make such a smash hit in “Escapade” and “The Great Ziegfeld,” she disappeared for over a week. As she had walked out of her house without even a toothbrush and with only four dollars in her pocket, both the studio and her servants were a little bit upset and worried.

    It turned out that Luise, too, had been on a jaunt following the sun and in her temperamental way hadn’t waited to tell anybody where she was going. She and her Scottie simply got in her little open roadster, with the top down, and drove from San Diego to Yosemite—which is a good many hundreds of miles. They slept in the car or in auto camps, and Luise hocked a bracelet she was wearing to get money to continue her trip because she loved it so she couldn’t bear to go home. With the top down, driving all day, she got all the sun she wanted and came back so brown and healthy that even the studio didn’t have the heart to say a word to her.

    MOST of the Hollywood stars who play tennis, play in shorts and halters so they can combine plenty of sun and air on their skins and some good fast exercise. Myrna Loy has her own tennis court and both she and her husband, Arthur Hornblow, play a lot. So do Fay Wray and her husband, John Monk Saunders.

    The whole idea of vacations, or time between pictures, is to get plenty of sun.

    Picture making, as perhaps outsiders don’t always realize, is hard physical work. It is also particularly nervous work. Acting is always a drain upon the emotions, whether you’re trying to get tears or laughter or suspense from your audience. For women it is often utterly exhausting work and leaves them nervous and drained at the end of each picture. Yet they have to start another one soon, and they have to be fresh and full of vigor and beauty, with healthy skins and clear eyes and superb figures.

    If you want to know how they do it, you have only to make the sun track through the hotels and resorts and beaches of California. They may go to Agua Caliente for the races, or to Del Monte or Pebble Beach for golf, or Honolulu for surf bathing, or Arrowhead for fishing and tennis, but wherever they go, they follow the sun and wherever they go, they spend hours of every day sun- and air-bathing.

    Looking them over, one decidedly concludes Hollywood has a new ideal figure.

  • CLEVELAND POLICE MOTORIZED (May, 1939)

    The scan doesn’t really do this ad justice. The colors are incredibly vibrant.

    CLEVELAND POLICE MOTORIZED

    CLEVELAND is prouder than ever of its Police Force which is now entirely motorized with the exception of the traffic detail.

    The city’s Emergency Mobile Patrol is making history by helping daily in the reduction of crime and traffic fatalities. The entire nation is focusing its attention on this masterly stroke of police-pioneering.

    Twelve motor units, fully equipped for double-duty service as ambulances and patrols, are manned by officers all of whom have hospital and first-aid training. Many of them are college graduates. The proved results in greater safety and service of this innovation in patrol work are spectacular.

    All twelve of these new Cleveland Police Patrols are International Model D-2 panel body trucks. And the performance of these Internationals is thoroughly in keeping with the reputation Internationals have established for economy, durability and dependability in every line of work.

    That kind of performance and that reputation explain why International Harvester sells more heavy-duty trucks, 2-ton and up, than any other three truck manufacturers combined.

    What does your business require in truck service or hauling? Whether you’re a grocer or a farmer, a baker or a builder, there’s an International designed for your special needs. The International Dealer or Branch nearest you is ready at any time to demonstrate International top performance, rock-bottom economy, and brilliant appearance.

    INTERNATIONAL HARVESTER COMPANY 180 North Michigan Avenue Chicago, Illinois

    INTERNATIONAL TRUCKS

  • Joy to the World | Cosmic Variance

    Atheists can be such uptight downers. And I say that completely seriously and non-sarcastically, despite being a card-carrying atheist myself.

    The latest example appears at the Illinois State Capitol, where someone from Freedom From Religion Foundation had the genius idea of erecting this sign among the holiday displays (via PZ):

    At the time of the winter solstice, let reason prevail. There are no gods, no devils, no angels, no heaven or hell. There is only our natural world. Religion is just myth and superstition that hardens hearts and enslaves minds.

    Well now, there’s an uplifting and positive message. I’m sure that lots of religious folks came along to read that sign, and immediately thought “Gee, whoever wrote that sounds so much smarter and more correct than me! I will throw off my superstitious shackles and join them in the celebration of reason.”

    There is a place to argue for one’s worldview — but not every single place. I happen to agree with all of the sentences on the sign above, but the decision to put in front and center in a holiday display merits a giant face-palm. (So does calling it “hate speech,” of course.) It’s like you’re introduced to someone at a party, and they immediately say “Wow, you’re ugly. And your clothes look like they were stolen off a homeless person. And you’re drinking a domestic beer, which shows a complete lack of sophistication.” I don’t know about you, but I’d be thinking — “Such taste and discernment! Here’s someone I need to get to know better.”

    Until atheists learn that they don’t need to take every possible opportunity to proclaim their own rationality in the face of everyone else’s stupidity, they will have a reputation as tiresome bores. They could have put up a sign that just gave some sort of joyful, positive message. Or something light-hearted and amusing. Or they could have just left the display alone entirely, and restrained the urge to argue in favor of waiting for some more appropriate venue. (Maybe they could start a blog or something.)

    Understanding how the real world works is an important skill. So is understanding human beings.


  • You Can Tramp All Day (Mar, 1922)

    Separate Sack Suspensory.

    You Can Tramp All Day

    You can do the hardest work or play without strain, chafing or pinching if you wear a Separate Sack Suspensory. The S.S.S. has no irritating leg straps, no oppressive band on the sack, no scratching metal slides. It is made just as nature intended.

    (Note illustration.)

    With the S.S.S. you always have a clean suspensory every morning. Each outfit has two sacks, you can clip one fast to the supporting straps while the other sack is cleaned. All sizes. Mailed in plain package on receipt of price. Money refunded If not satisfactory. Send stamp for booklet.

    MEYERS MANUFACTURING CO.

    65 Park Place Watertown, N. Y.

  • Tracking Santa on Christmas Eve

    If you are looking for something to do with the family today, don’t forget about tracking Santa with Norad. He’s been in several locations already today, from North Pole islands, to Australia and New Zealand and then up to Japan. You can watch the videos of Norad spotting Santa at the different locations and you can explore the North Pole village.

    tracking santa 2009

    I especially love all the military guys imparting news of Santa’s arrival and discussing different technical aspects of his journey, like the way they can figure out his speed by knowing how fast the Japanese train goes.

    If you’re still looking for something to do while you track Santa’s progress, you can find quite a few other online activities:

    • For Webkinz owners, there are a ton of Christmas things to do. Santakinz is still in the Webkinz clubhouse, taking last minute Christmas wishes from all the little Webkinz and Mrs. Birdy is giving out a treat in different rooms of the clubhouse.
    • Facebook games almost all seem to have Christmas gifts, decorations, etc.
    • Bellasara has a Winter festival going on.
    • PetPetPark has a massive Winter festival.
    • You can Elf Yourself.
    • North Pole has a lot of holiday games, like dressing a snowman.

    What is your favorite online hangout on Christmas eve?

    Post from: Blisstree

    Tracking Santa on Christmas Eve

  • Readers’ Picks: Xconomy San Diego’s Top 5 Stories of 2009

    Bruce V. Bigelow wrote:

    There are many differences between this new world of online media and the old world of ink-on-paper that I used to inhabit. So many, in fact, that sometimes I feel like the earthling in the blockbuster “Avatar” who must take archery lessons and learn how to live in an alien culture.

    One of the most important differences, though, is that Web-based technologies make it possible nowadays to measure exactly how many people view every story we publish. This can be a humbling experience, and it tends to upend some of those old-world media sensibilities that decreed by front-page fiat that certain stories—like lima beans—are important for readers to digest, whether they like them or not.

    So, with the end of 2009 drawing near, I can share some of the stories that attracted the most traffic over the past year at Xconomy San Diego site. I have listed them below, ranked according to popularity, so think of them in a way as Xconomy’s “People’s Choice Awards.” It’s a mixed bag, for sure, which suggests perhaps that we’re appealing to a diverse audience with a variety of interests in our coverage of what we like to call “the exponential economy.” Which is a way of saying, you know, when the facts speak for themselves, what else can an editor to do but interpret and analyze?

    The Untold Story of SAIC, Network Solutions, and the Rise of the Web

    This story was No. 1by a long shot. SAIC, the defense contractor that specializes in IT integration, research, and engineering projects, has maintained a low profile since it was founded in San Diego in 1969. So the story behind SAIC’s 1995 acquisition of Network Solutions Inc., which held exclusive rights to register Internet domain names was not widely known. Looking back, former SAIC executive Mike Daniels told me: “Nobody really understood that NSI basically had an exclusive contract to sell dot-com, dot-net, and dot-org to every human being on the planet…”

    San Diego’s Stem Cell Startup Reports Hair-Regrowth Results

    The bald truth is many people are yearning for information about new biomedical innovations with the potential to redress an age-old inequity—some people have hair and some don’t. San Diego-based Histogen, which was founded to develop a variety of medical therapies that use stem cells, reported in February that results of an overseas study of its ReGenica treatment for hair growth were encouraging. But a patent infringement lawsuit filed by SkinMedica, a Carlsbad, CA-rival, triggered a funding crisis and forced Histogen to lay off its entire workforce.

    Arena Eagerly Awaits Answer to $1Billion Question: Does it Have a Big Time Obesity Drug?

    Sometimes readers show more interest of the story published in advance of a big news announcement than in the announcement itself. That may have been the case with San Diego’s Arena Pharmaceuticals (NASDAQ: ARNA) in reporting the final results of a clinical trial for its experimental weight-loss pill, lorcaserin. The subsequent results were encouraging enough for Arena to file a new drug application earlier this week with the Food and Drug Administration.

    San Diego Biofuels Industry Gains Steam With R&D Consortium

    As a journalist, it’s always great to get the big scoop before the rest of the pack.In the case of the formation of the San Diego Center for Algae Biotechnology, I broke this story about four months before the official announcement. Steve Kay, the dean of Biological Sciences at UC San Diego, told me in January that SD-CAB was being organized as a consortium of academic and industry researchers, and represented a regional effort to establish a sustainable algae biofuels industry here in the next five to 10 years. When the formation of SD-CAB was officially announced on April 28, Cleantech San Diego chairman Jim Waring said, “Maybe someday, if the history of algae is ever written, this will be remembered as the day when it all started.”

    La Jolla Pharmaceutical Stock Crashes After Drug Fails in Pivotal Clinical Trial

    Luke’s breaking news story about the failed clinical trial of Riquent, a drug developed by San Diego’s La Jolla Pharmaceutical, noted that the announcement wiped out almost 90 percent of the San Diego-based company’s stock value. It also marked the beginning of a series of Xconomy stories that chronicled the layoffs, liquidation plan, and eventual merger of La Jolla Pharmaceutical with Adamis Pharmaceuticals of Del Mar, CA, earlier this month.







  • Should A Site Be Forced To Takedown Content If A Court Rules Against The User?

    Back in November, we wrote about how some were trying to get around Section 230 safe harbors to get content taken offline. Basically, since a website isn’t liable for the content posted by users, the upset party would file a lawsuit against the “user” often knowing that the user will never show up in court (the discussion suggested even filing it in a way against a “phantom author” to make sure no one will show up in court). Since the user doesn’t show up, a default judgment is entered, and then the lawyer has a court order stating that the content is defamatory and can go to the website demanding that the content be taken down.

    Now, in cases where the content actually is defamatory, this setup is probably fine (with some caveats). But in situations where the content isn’t defamatory and the default judgment is so “engineered,” it’s pretty ridiculous to then force a site to take down that content. And, in fact, Eric Goldman points out that, in one of these situations (default judgment entered, then with that in hand, requests were sent out demanding the content be taken down), a judge has sided with Ripoff Report (who didn’t want to take down the content) and said that the site has no obligation to remove the content, since “Ripoff Report’s relationship to the user is too “tenuous” (by entering into a user agreement for content publication) to constitute “acting in concert” under FRCP 65.”

    Goldman is troubled by this, as is Ben Sheffner, who sees it as a bad situation when there’s a “wrong” that has no remedy. After all, the original complainant “won” their case saying that there was defamatory content — but there appears to be no legal way to then get that content taken down! It’s certainly an odd situation, but the more I think about it, I think the complaint that Sheffner makes (that this is a problem with Section 230) is entirely misplaced.

    Section 230 works exactly as intended here: making sure that a third party is not made liable for the actions of others. The problem is with the default judgment process. It’s a situation where there’s really no “defense” for the content that was posted at all — which is Ripoff Report’s main concern. Now, there are plenty of reasons for why default judgments are granted when one party doesn’t show up, but it can lead to really bad results — such as potentially in these sorts of cases. Perhaps a more reasonable solution would be to set up a separate process that actually requires substantive review of the content before it can be forced offline — even if the supposedly liable party doesn’t show up. I recognize that opens up all sorts of other issues as well — but it seems like the most “fair” solution: don’t require takedown by third parties in default judgments, but include a separate process for establishing whether or not the content really needs to be removed. That leaves Section 230 intact, as it should be, and focuses the solution on the real issue.

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  • MDRNA Grabs $1M Bridge Loan

    Luke Timmerman wrote:

    MDRNA, the Bothell, WA-based company developing RNA interference technology, said today it has raised $1 million through a debt financing to ensure it has “sufficient resources” to meet its near-term goals of finding a partner or securing more financing in 2010. The company (NASDAQ: MRNA) said in a regulatory filing that it issued promissory notes at a 12 percent annual interest rate that come due on February 1, 2010 or possibly earlier. MDRNA also issued warrants to investors who may choose to buy more than 1 million shares of its stock at $1.02 a share over the next five years. MDRNA shares fell 8 percent on the news to 92 cents a share at 10 am Eastern time.







  • Largest Copper and Gold Mine Would Destroy Bristol Bay, Alaska

    bristolbaybear.jpg

    An international mining group is planning North America’s largest copper and gold mine at headwaters of Bristol Bay, Alaska. Environmentalists are outraged, as this is a “vital ecosystem” for salmon and other species. The National Resource Defense Council explains:

    The only way to extract the low-grade ore from the region would be to use a brutal and pollution-prone technique known as hard-rock mining, which includes powerful explosives and massive drilling equipment. At one of the proposed mines in Pebble, a remote, roadless area sandwiched between two national parks, spongy, lake-studded tundra would be scraped away, leaving a yawning two-mile-wide, 2,000-foot-deep pit in its place. This would be the largest open-pit mine in the world — wide enough to line up nine of the world’s longest cruise ships end to end and deep enough to swallow the Empire State Building. At a second mine, explosives would be used to create a series of underground cave-ins to extract ore.


  • Transparentius y la mejora de la seguridad vial

    transparentius.jpg
    La empresa Art Lebedev ha desarrollado un sistema llamado Transparentius en el cual, como se puede ver en la primera foto, a la hora de adelantar a un vehículo pesado tendremos la posibilidad de ver qué está ocurriendo delante del camión gracias a una cámara instalada en la parte frontal y a una pantalla instalada en la parte trasera (aunque lo parezca, no es que fabriquemos ahora los camiones con cristal).

    En España sigue habiendo muchas carreteras que sólo disponen de un carril y por las que pasa mucho tráfico: todos nos hemos visto “atrapados” detrás de un camión que no puede ir más rápido, con carreteras sinuosas que no permiten el correcto adelantamiento en condiciones de seguridad. Transparentius, con su rimbombante nombre, lo solucionaría.

    Como todo en la vida queda por ver a qué precio se puede desarrollar un sistema de este calibre. La clave estaría en que se probase su mejora en la seguridad y que alguna directiva europea lo estableciese como obligatorio para la mejora de la seguridad vial: como la llamada de emergencia eCall, los cinturones de seguridad antaño y demás elementos. Así la obligación de fabricarlo lo abarataría enormemente.

    Quizá en la conducción nocturna, o las conducciones en curvas cerradas Transparentius no logre buenos resultados: quizá también adelantar a un camión por la noche en en curvas cerradas incluya más peligro todavía y no sea recomendado. La tecnología está implantada, ahora queda ver si es efectiva y viable.

    Vía | MotorFull



  • New Research Finds Potential Inhibitors of Hepatitis C Replication

    By targeting Hepatitis C’s core protein, Scripps researchers have detected four promising compounds that could block viral reproduction.

    Scripps Researchers Identify Novel Hepatitis C Inhibitors
    Drug Discovery & Development – December 21, 2009

    Scientists from the Scripps Florida campus of The Scripps Research Institute and their colleagues at Boston University have described their discovery of several novel drug-like inhibitors of the hepatitis C virus (HCV). These new inhibitors have the potential to substantially widen the current options to treat HCV infection.

    Continue reading the entire article:
    http://www.dddmag.com/news-Scripps-Researchers-Identify-Novel-Hepatitis-C-Inhibitors-122109.aspx

  • What is stollen?

    StollenStollen is a traditional German Christmas bread. Sometimes, because the bread has such a rich texture and is so packed with fruit, it is described as a cake or a fruitcake. It starts with a  yeasted dough that is sweetened with sugar or honey and enriched with butter, to give it a soft texture. Spices or fruit zest are often added to the dough, as are nuts, dried fruits and candied fruits. The dough is wrapped around a log of marzipan before baking. It is traditionally shaped into a oblong loaf, but as stollen become more popular (as gift items, here in the US), you can sometimes see them in other shapes. The finished loaf is generously dusted with confectioner sugar before being sliced and served.

    Stollen is sweet and rich, but not as sweet as a regular Christmas cake or a plate full of sugar cookies. Unlike another traditional Christmas bread, panettone, it can be quite heavy, so it is best served in smaller slices where you can enjoy all the flavors in the loaf without being overwhelmed by too much marzipan in one go.

  • All I want for Christmas (for webOS)

    PalmDear Santa,

    I know you’re a busy guy and I really should have sent you this letter much earlier, but I know that if anybody could pull off the “Christmas miracle,” it’s you. I’ve tried my best to be a good blogger this year. I know sometimes I’ve aggravated my readers, but I said what I said because I thought it needed to be said. That’s being a good boy, right?

    Anyway, I hope that you get this list before you take off from your North Pole base of operations. Below is a list of what I’d really really really like to see on Christmas morning. If it’s not there, I understand, but if it is I promise to be extra good next year. I’m not trying to be greedy, I just want you to know that there’s a lot of stuff that would make me happy. Snow, though one of those things, does not count in the gift tally.

    read more

  • Apple Tablet rumors: WAY out of control

    Steve Jobs as Moses with the tablets from the Ten Commandments movie? Amazing lessons in spin: just create great stuff and ignore the press who then start feeding upon themselves.

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