{"id":151557,"date":"2010-01-07T15:20:11","date_gmt":"2010-01-07T20:20:11","guid":{"rendered":"tag:business.theatlantic.com,2010:\/\/3.33134"},"modified":"2010-01-07T15:08:15","modified_gmt":"2010-01-07T20:08:15","slug":"are-big-pharma-mergers-good-for-new-drugs","status":"publish","type":"post","link":"https:\/\/mereja.media\/index\/151557","title":{"rendered":"Are Big Pharma Mergers Good for New Drugs?"},"content":{"rendered":"<p>Merck and Schering-Plough, Wyeth and Pfizer. . .well, OK, everybody and Pfizer. There have been plenty of big mergers over the last few years in the drug industry, and they&#8217;ve always been accompanied by talk of economies of scale, critical mass, synergies, incredible opportunities that will come from merging two wonderful research pipelines and terrific development organizations. It&#8217;s enough to make you think that these things are good ideas.<\/p>\n<p>Until you look at the numbers, that is <br \/>A researcher named Bernard Munos at Eli Lilly has done that, though,<br \/>\nand reports his results in a well-respected industry forum, <i>Nature Reviews: Drug Discovery<\/i>.<br \/>\nThe reality is much closer to the one reported by the grumbling<br \/>\nscientists at these companies, rather than the one inhabited by the<br \/>\nCEOs. Companies that have gone through big mergers have been<br \/>\nunderperforming the industry averages for development of new drugs, not<br \/>\nthe other way around. Shareholders should perhaps take note next time<br \/>\nthey&#8217;re asked to approve another one of these deals.<\/p>\n<p>In fact,<br \/>\none of Muno&#8217;s main conclusions is that very little that drug companies<br \/>\nhave done over the last 60 years seems to have affected the underlying<br \/>\nrate of drug discovery. That process, in fact, models best as an<br \/>\nessentially random one, impervious to the best schemes of scientists<br \/>\nand MBAs alike. It&#8217;s possible that a number of factors have fought to a<br \/>\ndraw to make the figures come out that way, but several others have<br \/>\nalso remained static &#8211; the chances of a new molecule becoming a<br \/>\nblockbuster, for example. One thing that hasn&#8217;t stayed the same,<br \/>\nthough, is the cost of finding these drugs. Munos estimates that that&#8217;s<br \/>\nbeen going up at about 13% a year since the 1950s, and that trend shows<br \/>\nno sign of slowing down.<\/p>\n<p><i>Derek Lowe blogs from inside the drug labs at <a href=\"http:\/\/pipeline.corante.com\/\">In the Pipeline<\/a>.<\/i><br \/><br clear=\"both\" style=\"clear: both;\"\/><br \/>\n<br clear=\"both\" style=\"clear: both;\"\/><br \/>\n  <a style='font-size: 10px; color: maroon;' href='http:\/\/www.pheedcontent.com\/hostedMorselClick.php?hfmm=v3:e09b03e7faa07605f20e2c1c7fc8eea7:w%2B7GK1ciqfGUPRga9zXH5UPhZ%2BE735hoeJttL4RiA%2BLW0VBS%2BDerJiBZXtotQTuLIYdWhS2KdUXG'><img border='0' title='Email this Article' alt='Email this Article' src='http:\/\/images.pheedo.com\/images\/mm\/emailthis.png'\/><\/a><br \/>\n  <a style='font-size: 10px; color: maroon;' href='http:\/\/www.pheedcontent.com\/hostedMorselClick.php?hfmm=v3:f4fd2ce433a9ea31511d0c283f71aeaa:9clO8Q5dqcZDyGadglOPInFqgy3DXjxkyC%2F8duGl%2B%2BUSJ9nIHiMKvHiQbhtkvoMfk20GyTK%2BZTqR'><img border='0' title='Add to digg' alt='Add to digg' src='http:\/\/images.pheedo.com\/images\/mm\/digg.gif'\/><\/a><br \/>\n  <a style='font-size: 10px; color: maroon;' href='http:\/\/www.pheedcontent.com\/hostedMorselClick.php?hfmm=v3:19ad5c0aabb880f5acec6589bb2132b4:4nxf8sa%2F9l%2BrI1fcOQpezX%2FjeVXTATNxXrQGUzkXseMVdSOSJzPnpAnz4ZBe0f%2BeTa1GbL6B3gVb'><img border='0' title='Add to Reddit' alt='Add to Reddit' src='http:\/\/images.pheedo.com\/images\/mm\/reddit.png'\/><\/a><br \/>\n  <a style='font-size: 10px; color: maroon;' href='http:\/\/www.pheedcontent.com\/hostedMorselClick.php?hfmm=v3:0e2268dab13573c3912d38617dd8c700:kcwCD5%2Fpn5dX7Ip1g4mZ8O9OH7WVc0ueLQY4awPLdUWn%2FU1WeJTAG6X3wysxRqhvkhYG1FdXcvB4Bw%3D%3D'><img border='0' title='Add to Twitter' alt='Add to Twitter' src='http:\/\/images.pheedo.com\/images\/mm\/twitter.png'\/><\/a><br \/>\n  <a style='font-size: 10px; color: maroon;' href='http:\/\/www.pheedcontent.com\/hostedMorselClick.php?hfmm=v3:078109cf86a983c0a049361ab2fd49c9:I9lxHettCd3KWMW2zmy3CBUPUHX3DjPe%2BcKwd%2Fb9wdGplVsvcGCBs8B4x6bQ5EwRVrS85AarfacQ'><img border='0' title='Add to del.icio.us' alt='Add to del.icio.us' src='http:\/\/images.pheedo.com\/images\/mm\/delicious.gif'\/><\/a><br \/>\n  <a style='font-size: 10px; color: maroon;' href='http:\/\/www.pheedcontent.com\/hostedMorselClick.php?hfmm=v3:67ea68e7bf90b649d50e075fb3647be6:kth6YOYg%2FeS%2BIR2MajPETSCdK0Sj%2F6ri21x8ohFcKmw%2BU6cU7bWE%2BnoVSUPc2kU5x9u1DOGMHrgoVg%3D%3D'><img border='0' title='Add to StumbleUpon' alt='Add to StumbleUpon' src='http:\/\/images.pheedo.com\/images\/mm\/stumbleit.gif'\/><\/a><br \/>\n  <a style='font-size: 10px; color: maroon;' href='http:\/\/www.pheedcontent.com\/hostedMorselClick.php?hfmm=v3:1e2eeb92f9d4e3900265783237e63b5e:cUgTXEXGdpK0vJc0rDlqwV%2BlRCgaoOMxQ681jjUkadXRPxpyLFCOoLGbFVXb8mb%2FBNOUTeVGSa9LoA%3D%3D'><img border='0' title='Add to Facebook' alt='Add to Facebook' src='http:\/\/images.pheedo.com\/images\/mm\/facebook.gif'\/><\/a><br \/>\n<br clear=\"both\" style=\"clear: both;\"\/><br \/>\n<a href=\"http:\/\/ads.pheedo.com\/click.phdo?s=3e7d0175d2cf645b2a998e8c8b23cab3&#038;p=1\"><img decoding=\"async\" alt=\"\" style=\"border: 0;\" border=\"0\" src=\"http:\/\/ads.pheedo.com\/img.phdo?s=3e7d0175d2cf645b2a998e8c8b23cab3&#038;p=1\"\/><\/a><br \/>\n<img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"0\" width=\"0\" border=\"0\" style=\"display:none\" src=\"http:\/\/a.rfihub.com\/eus.gif?eui=2225\"\/><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/AtlanticBusinessChannel\/~4\/SmuK49zoqPk\" height=\"1\" width=\"1\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Merck and Schering-Plough, Wyeth and Pfizer. . .well, OK, everybody and Pfizer. There have been plenty of big mergers over the last few years in the drug industry, and they&#8217;ve always been accompanied by talk of economies of scale, critical mass, synergies, incredible opportunities that will come from merging two wonderful research pipelines and terrific [&hellip;]<\/p>\n","protected":false},"author":2160,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-151557","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/151557","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/users\/2160"}],"replies":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/comments?post=151557"}],"version-history":[{"count":0,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/151557\/revisions"}],"wp:attachment":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/media?parent=151557"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/categories?post=151557"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/tags?post=151557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}