{"id":190734,"date":"2010-01-17T10:48:52","date_gmt":"2010-01-17T15:48:52","guid":{"rendered":"http:\/\/www.diabetesforums.com\/forum\/type-2-diabetes\/47700-joslin-reports-mechanism-beta.html"},"modified":"2010-01-17T10:48:52","modified_gmt":"2010-01-17T15:48:52","slug":"joslin-reports-mechanism-for-beta-cell-damage","status":"publish","type":"post","link":"https:\/\/mereja.media\/index\/190734","title":{"rendered":"Joslin reports mechanism for beta cell damage"},"content":{"rendered":"
From this week’s "Diabetes in Control":<\/p>\n
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\t\t\t\tJoslin Identifies Source of Beta Cell Damage<\/b><\/p>\n

Scientists at the Joslin Diabetes Center, Boston, MA, led by Principal Investigator Robert Stanton, M.D., have discovered that high blood glucose levels damage a key enzyme that guards insulin-producing beta cells. Their surprising finding raises hopes of finding drugs that protect the enzyme, and thus the beta cells and their insulin production. The discovery focuses on a cellular process known as "oxidative stress."<\/p>\n

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Joslin Diabetes Center Release Here<\/a>. No specific data given, but Jenny Ruhl, over at Blood Sugar 101, cites to an Italian study that indicated impaired beta cell functioning in folks with two-hour OGTTs over 100: <\/p>\n

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\t\t\t\tIn lean NGTs with a 2-h plasma glucose concentration (2-h PG) between 5.6 and 6.6 and between 6.7 and 7.7 mmol\/l, there was a progressive decline in I\/G\u00f7IR compared with NGTs with a 2-h PG less than 5.6 mmol\/l.<\/p>\n

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From this week’s "Diabetes in Control": Quote: Joslin Identifies Source of Beta Cell Damage Scientists at the Joslin Diabetes Center, Boston, MA, led by Principal Investigator Robert Stanton, M.D., have discovered that high blood glucose levels damage a key enzyme that guards insulin-producing beta cells. Their surprising finding raises hopes of finding drugs that protect […]<\/p>\n","protected":false},"author":3271,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-190734","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/190734","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/users\/3271"}],"replies":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/comments?post=190734"}],"version-history":[{"count":0,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/190734\/revisions"}],"wp:attachment":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/media?parent=190734"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/categories?post=190734"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/tags?post=190734"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}