{"id":236518,"date":"2010-01-27T10:00:56","date_gmt":"2010-01-27T15:00:56","guid":{"rendered":"http:\/\/www.aboutlawsuits.com\/?p=7832"},"modified":"2010-01-27T10:00:56","modified_gmt":"2010-01-27T15:00:56","slug":"seroquel-weight-gain-side-effects-suppressed-by-astrazeneca","status":"publish","type":"post","link":"https:\/\/mereja.media\/index\/236518","title":{"rendered":"Seroquel Weight-Gain Side Effects Suppressed by AstraZeneca"},"content":{"rendered":"

A former high-ranking AstraZeneca employee has admitted that the pharmaceutical company knew about the potential weight-gain side effects of Seroquel<\/a>, but pressured medical staff to sign off on claims that the antipsychotic drug was weight neutral. <\/span><\/p>\n

John Blenkinsopp, the company\u2019s former U.K. medical advisor, told the BBC in an interview<\/a> that AstraZeneca\u2019s marketing wing pressured him to sign off on a claim that Seroquel was weight neutral, threatening his career when he refused. <\/p>\n

The allegations come as AstraZeneca faces thousands of Seroquel lawsuits<\/a> claiming that users developed diabetes and other injuries as a result of the drug makers failure to warn about the weight gain risks. The first Seroquel trial<\/a> is currently expected to begin next month in New Jersey state court.<\/p>\n

Seroquel<\/a> (quetiapine fumarate) is an atypical-antipsychotic that is a top selling drug for AstraZeneca, generating nearly $5 billion a year in sales. Approved by the FDA in 1997 for the treatment of schizophrenia, it is also commonly used off-label for treatment of anxiety, obsessive dementia, compulsive disorders and autism. Seroquel has been used by more than 19 million people worldwide.<\/p>\n

Blenkinsopp, who left the company in 2000, claims that he never signed off on Seroquel\u2019s weight neutral claims; a decision that AstraZeneca marketing staff allegedly told Blenkinsopp would limit his career. As a result, while Seroquel consistently was advertised as being weight neutral in the U.S., only one ad in the U.K. made that claim.<\/p>\n

\u201cThey came at me with a number of potential claims, all of which were trying to intimate that Seroquel was not associated with weight gain. None of which I would approve,\u201d Blenkinsopp told the BBC. \u201cThe data pointed in the opposite direction.\u201d<\/p>\n

Blenkinsopp said he showed other AstraZeneca officials their own data, which showed that Seroquel caused weight gain, but even after seeing evidence to the contrary, they continued to push for him to agree that the drug was weight neutral.<\/p>\n

According to internal AstraZeneca documents uncovered during the Seroquel litigation<\/a>, a 2001 letter from a marketing official revealed that the drug maker had a global strategy aimed at suppressing the Seroquel weight gain side effects<\/a>, casting the drug as weight-neutral years after clinical evidence demonstrated significant risks of weight gain among users, which could lead to diabetes and other serious health problems.<\/p>\n","protected":false},"excerpt":{"rendered":"

A former high-ranking AstraZeneca employee has admitted that the pharmaceutical company knew about the potential weight-gain side effects of Seroquel, but pressured medical staff to sign off on claims that the antipsychotic drug was weight neutral. John Blenkinsopp, the company\u2019s former U.K. medical advisor, told the BBC in an interview that AstraZeneca\u2019s marketing wing pressured […]<\/p>\n","protected":false},"author":3957,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-236518","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/236518","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/users\/3957"}],"replies":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/comments?post=236518"}],"version-history":[{"count":0,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/236518\/revisions"}],"wp:attachment":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/media?parent=236518"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/categories?post=236518"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/tags?post=236518"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}