{"id":276729,"date":"2010-02-04T07:00:32","date_gmt":"2010-02-04T12:00:32","guid":{"rendered":"http:\/\/blogs.discovermagazine.com\/discoblog\/?p=6388"},"modified":"2010-02-04T07:00:32","modified_gmt":"2010-02-04T12:00:32","slug":"ncbi-rofl-%e2%80%9cback-and-forth-forever%e2%80%9d-or-diy-poop-therapy-discoblog","status":"publish","type":"post","link":"https:\/\/mereja.media\/index\/276729","title":{"rendered":"NCBI ROFL: \u201cBack and forth forever\u201d (or, DIY poop therapy). | Discoblog"},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft size-full wp-image-6406\" title=\"3155783018_fdaf220ca1\" src=\"http:\/\/blogs.discovermagazine.com\/discoblog\/files\/2010\/02\/3155783018_fdaf220ca1.jpg\" alt=\"3155783018_fdaf220ca1\" width=\"184\" height=\"247\"\/>Success of self-administered home fecal transplantation for chronic Clostridium difficile infection.<\/p>\n<p>&#8220;Clostridium difficile infection (CDI) can relapse in patients with significant comorbidities. A subset of these patients becomes dependent on oral vancomycin therapy for prolonged periods with only temporary clinical improvement. These patients incur significant morbidity from recurrent diarrhea and financial costs from chronic antibiotic therapy. We sought to investigate whether <strong>self- or family-administered fecal transplantation<\/strong> could be used to definitively treat refractory CDI. <span id=\"more-6388\"><\/span>We report a case series (n=7) where 100% clinical success was achieved in treating these individuals with up to 14 months follow up.&#8221;<\/p>\n<p><a rel=\"nofollow\"  href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20117243\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-6390\" title=\"poop_back_and_forth\" src=\"http:\/\/blogs.discovermagazine.com\/discoblog\/files\/2010\/02\/poop_back_and_forth.jpg\" alt=\"poop_back_and_forth\" width=\"449\" height=\"199\"\/><\/a><\/p>\n<p><em>Thanks to Caryn for today&#8217;s ROFL!<\/em><br \/>\n<em>Photo: flickr\/<a rel=\"nofollow\"  href=\"http:\/\/www.flickr.com\/photos\/littledebbie11\/3155783018\/\">\u2605Debs\u2605<\/a><\/em><\/p>\n<p>And in case you didn&#8217;t get our title reference:<br \/>\n<iframe loading=\"lazy\" class=\"embeddedvideo\" type=\"application\/x-shockwave-flash\" width=\"425\" height=\"344\" src=\"http:\/\/www.youtube.com\/v\/KQoJo81lujk&amp;hl=en_US&amp;fs=1&amp;\"><\/iframe><\/p>\n<p>Related content:<br \/>\nDiscoblog:<a rel=\"nofollow\" title=\"Permanent Link: NCBI ROFL: One rat, one cup.\"  href=\"http:\/\/blogs.discovermagazine.com\/discoblog\/2009\/09\/07\/one-rat-one-cup\/\"> NCBI ROFL: One rat, one cup.<\/a><br \/>\nDiscoblog:<a rel=\"nofollow\" title=\"Permanent Link: NCBI ROFL: Rectal impaction following enema with concrete mix.\"  href=\"http:\/\/blogs.discovermagazine.com\/discoblog\/2009\/10\/23\/rectal-impaction-following-enema-with-concrete-mix\/\"> NCBI ROFL: Rectal impaction following enema with concrete mix.<\/a><br \/>\nDiscoblog: <a rel=\"nofollow\" title=\"Permanent Link: NCBI ROFL: Rectal oven mitt.\"  href=\"http:\/\/blogs.discovermagazine.com\/discoblog\/2009\/09\/17\/rectal-oven-mitt\/\">NCBI ROFL: Rectal oven mitt.<\/a><\/p>\n<p><a rel=\"nofollow\"  href=\"http:\/\/feedads.g.doubleclick.net\/~a\/9SCUHHqnlDjnGW8a0ylJoScZ0hE\/0\/da\"><img decoding=\"async\" src=\"http:\/\/feedads.g.doubleclick.net\/~a\/9SCUHHqnlDjnGW8a0ylJoScZ0hE\/0\/di\" border=\"0\" ismap><\/a><br \/>\n<a rel=\"nofollow\"  href=\"http:\/\/feedads.g.doubleclick.net\/~a\/9SCUHHqnlDjnGW8a0ylJoScZ0hE\/1\/da\"><img decoding=\"async\" src=\"http:\/\/feedads.g.doubleclick.net\/~a\/9SCUHHqnlDjnGW8a0ylJoScZ0hE\/1\/di\" border=\"0\" ismap><\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/DiscoverMag\/~4\/8UT0DTvzPN0\" height=\"1\" width=\"1\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Success of self-administered home fecal transplantation for chronic Clostridium difficile infection. &#8220;Clostridium difficile infection (CDI) can relapse in patients with significant comorbidities. A subset of these patients becomes dependent on oral vancomycin therapy for prolonged periods with only temporary clinical improvement. These patients incur significant morbidity from recurrent diarrhea and financial costs from chronic antibiotic [&hellip;]<\/p>\n","protected":false},"author":641,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-276729","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/276729","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/users\/641"}],"replies":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/comments?post=276729"}],"version-history":[{"count":0,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/276729\/revisions"}],"wp:attachment":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/media?parent=276729"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/categories?post=276729"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/tags?post=276729"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}