{"id":336160,"date":"2010-02-18T14:53:51","date_gmt":"2010-02-18T19:53:51","guid":{"rendered":"http:\/\/blogs.wsj.com\/health\/2010\/02\/18\/fda-discourages-use-of-some-asthma-drugs-after-years-of-review\/"},"modified":"2010-02-18T14:53:51","modified_gmt":"2010-02-18T19:53:51","slug":"fda-discourages-use-of-some-asthma-drugs-after-years-of-review","status":"publish","type":"post","link":"https:\/\/mereja.media\/index\/336160","title":{"rendered":"FDA Discourages Use of Some Asthma Drugs After Years of Review"},"content":{"rendered":"<p><img decoding=\"async\" src=\"http:\/\/online.wsj.com\/media\/symbicort_CV_20081212144714.jpg\" alt=\"ASTHMA\" align=\"right\"\/>Safety experts advising the FDA have been sending up flares about various asthma drugs for several years. <a href=\"http:\/\/blogs.wsj.com\/health\/2007\/11\/28\/fda-panel-more-warnings-on-asthma-drugs-for-kids\/\" >In 2007<\/a>, a panel said GlaxoSmithKline\u0092s Serevent and Advair should carry a warning about risks to children. <a href=\"http:\/\/blogs.wsj.com\/health\/2008\/12\/12\/why-an-fda-panel-saw-asthma-drugs-differently\/\" >In 2008<\/a>, experts said Serevent and Norvartis&#8217;s Foradil shouldn\u0092t be used for asthma any more.<\/p>\n<p>Today, the FDA itself said it had heard enough. The agency said it plans to impose new &#8220;safety controls&#8221;  over those three drugs as well as AstraZeneca&#8217;s Symbicort, warning that they should be for the shortest time possible to obtain asthma control and then discontinued. Here&#8217;s the FDA <a href=\"http:\/\/www.fda.gov\/Drugs\/DrugSafety\/PostmarketDrugSafetyInformationforPatientsandProviders\/ucm200776.htm\" >announcement<\/a> and a <a href=\"http:\/\/www.fda.gov\/Drugs\/DrugSafety\/InformationbyDrugClass\/ucm200719.htm\" >Q&#038;A<\/a> from the agency.<\/p>\n<p>The drugs are so-called long-acting beta-agonists that are used by about six million asthma patients. The FDA said single-agent LABAs should be taken along with other inhaled drugs called corticosteroids. Advair and Symbicort come with LABAs and steroids combined.<\/p>\n<p>The medications already carry various warnings but the new wording will be tougher in a bid to cut down on overall use and avoid improper usage that can cause hospitalizations and death, the FDA said. Some 22 million Americans have asthma, a chronic condition marked by narrowing of the airways.<\/p>\n<p><a href=\"http:\/\/online.wsj.com\/article\/BT-CO-20100218-713792.html?mod=WSJ_latestheadlines\" >Dow Jones Newswires<\/a> and <a href=\"http:\/\/in.reuters.com\/article\/governmentFilingsNews\/idINN1820469720100218\" >Reuters<\/a> have more details.<\/p>\n<p><em>Photo: AstraZeneca<\/em><\/p>\n<p><a href=\"http:\/\/feedads.g.doubleclick.net\/~at\/rAEaLnEVe1jqKKZYpCCoqv6XzdU\/0\/da\"><img decoding=\"async\" src=\"http:\/\/feedads.g.doubleclick.net\/~at\/rAEaLnEVe1jqKKZYpCCoqv6XzdU\/0\/di\" border=\"0\" ismap=\"true\"><\/img><\/a><br \/>\n<a href=\"http:\/\/feedads.g.doubleclick.net\/~at\/rAEaLnEVe1jqKKZYpCCoqv6XzdU\/1\/da\"><img decoding=\"async\" src=\"http:\/\/feedads.g.doubleclick.net\/~at\/rAEaLnEVe1jqKKZYpCCoqv6XzdU\/1\/di\" border=\"0\" ismap=\"true\"><\/img><\/a><\/p>\n<div class=\"feedflare\">\n<a href=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?a=uZNK_D8vLKc:zHVHhgpOrJY:yIl2AUoC8zA\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?d=yIl2AUoC8zA\" border=\"0\"><\/img><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?a=uZNK_D8vLKc:zHVHhgpOrJY:D7DqB2pKExk\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?i=uZNK_D8vLKc:zHVHhgpOrJY:D7DqB2pKExk\" border=\"0\"><\/img><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?a=uZNK_D8vLKc:zHVHhgpOrJY:F7zBnMyn0Lo\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?i=uZNK_D8vLKc:zHVHhgpOrJY:F7zBnMyn0Lo\" border=\"0\"><\/img><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?a=uZNK_D8vLKc:zHVHhgpOrJY:V_sGLiPBpWU\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?i=uZNK_D8vLKc:zHVHhgpOrJY:V_sGLiPBpWU\" border=\"0\"><\/img><\/a> <a href=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?a=uZNK_D8vLKc:zHVHhgpOrJY:qj6IDK7rITs\"><img decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~ff\/wsj\/health\/feed?d=qj6IDK7rITs\" border=\"0\"><\/img><\/a>\n<\/div>\n<p><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/feeds.feedburner.com\/~r\/wsj\/health\/feed\/~4\/uZNK_D8vLKc\" height=\"1\" width=\"1\"\/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Safety experts advising the FDA have been sending up flares about various asthma drugs for several years. In 2007, a panel said GlaxoSmithKline\u0092s Serevent and Advair should carry a warning about risks to children. In 2008, experts said Serevent and Norvartis&#8217;s Foradil shouldn\u0092t be used for asthma any more. Today, the FDA itself said it [&hellip;]<\/p>\n","protected":false},"author":792,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-336160","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/336160","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/users\/792"}],"replies":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/comments?post=336160"}],"version-history":[{"count":0,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/336160\/revisions"}],"wp:attachment":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/media?parent=336160"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/categories?post=336160"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/tags?post=336160"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}