{"id":375548,"date":"2010-03-01T11:32:04","date_gmt":"2010-03-01T16:32:04","guid":{"rendered":"http:\/\/www.szone.us\/f86\/plant-derivative-may-reduce-resistance-breast-cancer-drug-40152\/"},"modified":"2010-03-01T11:32:04","modified_gmt":"2010-03-01T16:32:04","slug":"plant-derivative-may-reduce-resistance-to-breast-cancerdrug","status":"publish","type":"post","link":"https:\/\/mereja.media\/index\/375548","title":{"rendered":"Plant Derivative May Reduce Resistance To Breast Cancer*Drug"},"content":{"rendered":"<div>02.28.10 07:01 PM<\/p>\n<p><img decoding=\"async\" src=\"http:\/\/pictures.directnews.co.uk\/liveimages\/Breakthrough+Breast+Cancer+pink+ribbon+badge_1961_19624824_0_0_7043242_300.jpg\" border=\"0\" alt=\"\" \/>A recent study has found that combining tamoxifen, the most prescribed breast cancer drug in the world, with a compound originating from the feverfew plant may help prevent initial or future resistance to the medication. <\/p>\n<p>&quot;A solution to tamoxifen resistance is sorely needed, and if a strategy like this can work, it would make a difference in our clinical care of breast cancer,&quot; said Robert Clarke, the study&#8217;s lead investigator.<\/p>\n<p>Approximately 70 percent of newly diagnosed breast cancer patients are prescribed tamoxifen, although half of those individuals do not initially respond to the drug due to an aggressive resistance. <\/p>\n<p>In the study, researchers from the Georgetown University Medical Center found that the purified chemical known as parthenolide, a derivative of feverfew, was able to successfully block the activity of nuclear factor kappa B (NF- ?B), a protein complex that is often over-expressed in breast cancer patients, leading to the body&#8217;s resistance to tamoxifen.<\/p>\n<p>Although the researchers are optimistic, they believe that it is too early to recommend the drug combination to patients as they are still unsure of its long-term benefits. <br \/>\n<img decoding=\"async\" src=\"http:\/\/feeds.directnews.co.uk\/feedtrack\/justcopyright.gif?feedid=1961&amp;itemid=19624824\" border=\"0\" alt=\"\" \/><\/p>\n<p><a href=\"http:\/\/www.personalliberty.com\/news\/plant-derivative-may-reduce-resistance-to-breast-cancer-drug-19624824\/\" >http:\/\/www.personalliberty.com\/news\/&#8230;drug-19624824\/<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>02.28.10 07:01 PM A recent study has found that combining tamoxifen, the most prescribed breast cancer drug in the world, with a compound originating from the feverfew plant may help prevent initial or future resistance to the medication. &quot;A solution to tamoxifen resistance is sorely needed, and if a strategy like this can work, it [&hellip;]<\/p>\n","protected":false},"author":4498,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-375548","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/375548","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/users\/4498"}],"replies":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/comments?post=375548"}],"version-history":[{"count":0,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/375548\/revisions"}],"wp:attachment":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/media?parent=375548"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/categories?post=375548"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/tags?post=375548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}