{"id":85433,"date":"2009-12-16T14:48:59","date_gmt":"2009-12-16T19:48:59","guid":{"rendered":"http:\/\/www.technologytransfertactics.com\/content\/?p=5527"},"modified":"2009-12-16T14:48:59","modified_gmt":"2009-12-16T19:48:59","slug":"novel-mouthwash-formulation-protects-against-tooth-decay","status":"publish","type":"post","link":"https:\/\/mereja.media\/index\/85433","title":{"rendered":"Novel mouthwash formulation protects against tooth decay"},"content":{"rendered":"<p>A research team at the University of Nebraska Medical Center in Omaha has developed a mouthwash formulation that may provide long-term protection against tooth decay. Led by Dong Wang, PhD, associate professor of pharmaceutical science in the UNMC College of Pharmacy, the team developed a drug delivery system to carry antimicrobial agents directly to teeth. A major contributing factor to dental cavities is overpopulation of acid-producing bacteria in biofilm present on the tooth surface, eventually causing dental decay. Wang&#8217;s formulation would bind to the tooth surface and gradually release antimicrobials against cavity-forming bacteria such as Streptococcus mutans. &#8220;The beauty of this design is the simplicity,&#8221; he says. &#8220;All one may have to do is their routine oral hygiene procedure and then rinse with the formulation that we have developed. It could protect the teeth over a long period of time.&#8221; A study demonstrating the formulation was published in <a href=\"http:\/\/aac.asm.org\/cgi\/content\/abstract\/53\/11\/4898\" ><em>Antimicrobial Agents and Chemotherapy<\/em><\/a>.<\/p>\n<p>Such a product also could have far-reaching implications for older adults in nursing homes who don&#8217;t have good access to dental care and for those at increased risk of heart disease. A Patent Cooperation Treaty (PCT) patent application has been filed on the technology through UNeMed, the technology transfer arm of UNMC. Wang and colleagues are seeking funds to support a clinical trial and a cGMP (current Good Manufacturing Practice) facility to manufacture the formulation.<\/p>\n<p>Source: <a href=\"http:\/\/www.healthnewsdigest.com\/news\/Dental_330\/New_Mouthwash_Formulation_that_Protects_Against_Tooth_Decay.shtml\" >Health News Digest<\/a><\/p>\n<p><br class=\"spacer_\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A research team at the University of Nebraska Medical Center in Omaha has developed a mouthwash formulation that may provide long-term protection against tooth decay. Led by Dong Wang, PhD, associate professor of pharmaceutical science in the UNMC College of Pharmacy, the team developed a drug delivery system to carry antimicrobial agents directly to teeth. [&hellip;]<\/p>\n","protected":false},"author":67,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-85433","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/85433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/users\/67"}],"replies":[{"embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/comments?post=85433"}],"version-history":[{"count":0,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/posts\/85433\/revisions"}],"wp:attachment":[{"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/media?parent=85433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/categories?post=85433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mereja.media\/index\/wp-json\/wp\/v2\/tags?post=85433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}