Natural GMOs Part 61: bornaviruses lurk in the human genome

UT Arlington genome biologist reports on surprising evolutionary discovery
News Release — 6 January 2010

A recent study on the 8 percent of human DNA that is derived from viruses may show a cause of cell mutation and psychiatric disorders such as schizophrenia and mood disorders, according to an article by The University of Texas at Arlington biology professor Cédric Feschotte published in the Jan. 7, 2010, issue of Nature magazine.

The study — led by Professor Keizo Tomonaga at Osaka University in Japan — revealed that the genomes of humans and other mammals contain DNA derived from the insertion of bornaviruses, RNA viruses whose replication takes place in the nucleus of cells. It was the first to show sequences derived from a virus other than retroviruses. Researchers have known since 2001 that 8 percent of human genetic material is derived from retroviruses.

UTA News Center