Author: Marijke Durning, RN

  • When Is a Teaspoon Not a Teaspoon?

    Every parent knows the drill: giving a liquid prescription or over-the-counter medication to a child requires measuring out the exact amount. Doses can range from a fraction of a teaspoon to one or more tablespoons, but whatever the dose, it’s vital that the children receive the prescribed amount. But, do they? Not always, says the result of a study just published in the Annals of Internal Medicine.

    spoonsIdeally, people dispensing liquid medications should be using measuring spoons meant for that purpose; they are available at most drug stores either in the stock or by asking the pharmacist. In reality, many people end up using kitchen measuring spoons, which may be generally ok for cooking, but not for something as precise as medications. Another practice is some people use bigger spoons so they don’t spill, and they eyeball the amount, figuring they can judge what a teaspoon of liquid looks like in a tablespoon, for example.

    Of course, the problem isn’t confined to just children. There are medications for adults that come in liquid form and many seniors can no longer chew medications and they may be using liquid medications more frequently.

    For this reason, researchers looked at the accuracy of liquid medication dosing among 195 college students using a liquid cough medicine. The students were asked to pour one teaspoon of the medication in a teaspoon. They were then asked to pour the same amount, 5 milliliters (mL), into larger spoons (15 mL and 45 mL), judging by eye when they had a teaspoon.

    spoonWhen the researchers looked at how much the students poured, they found that they underestimated most often in the 15-mL spoon (average 4.58 mL) and overestimated in the 45-mL spoon (5.58 mL). This was despite their confidence that they had accurately poured the dosage.

    This means if the students were taking the medication with the smaller spoon, they were undermedicating and if they were using the larger spoon, they were overmedicating. Both can have significant effects, depending on the medications.

    The moral of the story? Always use the correct measuring spoon or medication cup to take or give liquid medication.

    ~~~

    Images: MorgueFile.com

    Post from: Blisstree

    When Is a Teaspoon Not a Teaspoon?

  • Antidepressants Only for Severe Depression

    If you are experiencing mild or moderate depression, chances are antidepressant medications won’t be any help to you, say researchers. These medications are only useful to those who are living with severe depression.

    Millions of prescriptions for antidepressants are being written now that they’ve become so available and more accepted as treatment in today’s society. However, there have been many criticisms about how often the medications are being prescribed and for whom. It is often suggested that, although there are people who can truly benefit from antidepressant medications, there are those who would be able to manage by discussing their depression with their doctor or a counselor and making lifestyle changes.

    Jay C. Fournier, M.A., of the University of Pennsylvania, Philadelphia, and colleagues reviewed six large-scale studies, involving 718 patients altogether, that looked at the effectiveness of antidepressants in treating depression. The review findings were published yesterday in JAMA.

    Perhaps not surprisingly, the researchers found that the effectiveness of the antidepressants depending strongly on how severe the patients’ depression was to begin with.

    iStock_depressedWomanThe authors found that the efficacy of ADM treatment for depression varied considerably, depending on symptom severity. “True drug effects (an advantage of ADM over placebo) were nonexistent to negligible among depressed patients with mild, moderate, and even severe baseline symptoms, whereas they were large for patients with very severe symptoms.

    There is bound to be controversy over this finding because there always seems to be when studies like this come out. Some people would like to have an instant cure for depression, but that’s just not possible. Recovering from depression and managing to live with it takes a lot of work, whether it is through medication or other therapies.

    ~~~

    Post from: Blisstree

    Antidepressants Only for Severe Depression

  • Shared Hospital Rooms Raise Infection Risk

    I didn’t put this in the Duh Study category, but it is rather obvious, I would think: “Queen’s University study concludes private rooms are safer.”

    Back in “the old days,” many hospitals didn’t have private rooms and patients were mostly in wards – a large room with bed after bed, lining the walls. They had male hospital bedswards and female wards. Then, wards became smaller and four-bedded rooms were more the norm, along with semi-private (two-bedded rooms) and private rooms.

    Hospitals now are often built to limit shared rooms as much as possible, for patient privacy and to limit the spread of disease. A study, just published in the on-line version of the American Journal of Infection Control, reports that having a roommate or roommates increases your risk of catching an infection or infectious disease.

    This may not have been a big issue in years gone by, but with the rising concerns of superbugs becoming stronger and more prevalent, it is important to try to eliminate as many risky situations as possible. And, if this means making all hospital rooms private, then maybe this is the way to go.

    An all-private room facility isn’t cheap and it is more difficult for the nursing staff to monitor all the patients if they’re not adequately staffed, but the cost of treating the so-called superbugs and the economic cost (lost wages, for example) may become astronomical.

    According to the study’s authors:

    “If you’re in a two, three or four-bedded room, each time you get a new roommate your risk of acquiring these serious infections increases by 10 per cent,” says Dr. Zoutman, professor of Community Health and Epidemiology at Queen’s. “That’s a substantial risk, particularly for longer hospital stays when you can expect to have many different roommates.”

    ~~~

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    Post from: Blisstree

    Shared Hospital Rooms Raise Infection Risk

  • St. John’s Wort Doesn’t help IBS

    People who live with irritable bowel syndrome (IBS) are often faced with trial-and-error to find treatments that work for them. One type of treatment that can be successful for some people with IBS is using antidepressant medications. This isn’t to say that IBS is related to depression, but some antidepressant medications have stjohnswortother properties, such as providing pain relief from chronic pain. In the case of IBS, the antidepressants may work because there are chemical transmitters in the brain that are also present in the colon.

    When it comes to antidepressants, some people swear by the supplement St. John’s Wort (Hypericum perforatum). Because of the antidepressant properties found by some people, researchers wanted to see if St. John’s Wort would be a reasonable treatment for IBS, as well.

    The researchers studied 70 people (86% women) with IBS. They were divided into two groups and randomized to receive St. John’s Wort or a placebo. The medications were taken for three months.

    Symptoms of IBS, such as stomach pain, diarrhea, constipation and bloating were observed. When the researchers assessed the incidence of the symptoms in both groups, they found that the people who took the placebos were actually doing better than those who took the St. John’s Wort.

    According to the study’s authors:

    “The challenge with IBS is that there is no cure, no one treatment tends to be wholly effective and some treatments come with significant side effects,” explains Dr. Saito [M.D., M.P.H., gastroenterologist and lead physician scientist]. “However, well-designed studies of herbal supplements are important so that physicians and patients can make informed decisions about which supplements to recommend or try. Studies of alternative treatments are generally lacking and patients are forced to use a “trial and error” approach to over-the-counter treatments for their IBS.”

    ~~~

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    Post from: Blisstree

    St. John’s Wort Doesn’t help IBS

  • Disappointment: Lung Cancer Study Halted

    A study looking at the effectiveness of the drug figitumumab in treating late-stage lung cancer has been stopped by the manufacturer, Pfizer Inc.

    Late-stage lung cancer is difficult to treat and researchers are continuously looking for different drug combinations that could help increase the survival rate of the lungsdisease. This particular study looked at figitumumab in combination with two other chemotherapy agents, paclitaxel and carboplatin. The researchers were comparing the three-drug combination to paclitaxel plus carboplatin alone.

    In October 2009, Pfizer stopped patient recruitment into the study. Independent monitors had found disturbing outcomes, serious adverse events including deaths, among patients who had been receiving figitumumab.

    Although the study’s discontinuation is a disappointment for those who had high hopes for this treatment, not all is lost when a study is stopped. Valuable data had been collected over the course of the study and the researchers may be able to glean information from the data that could be helpful in future studies.

    Other pharmaceutical companies are continuing to look at using figitumumab for other cancers, because it is possible that although it was not acceptable for late-stage lung cancer, it may be a good treatment for another type.

    ~~~

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    Post from: Blisstree

    Disappointment: Lung Cancer Study Halted

  • Sinus Surgery Improves Quality of Life

    Sometimes short headlines can’t say what you really want them to say. Sinus surgery can improve your quality of life, but only if you have a condition that needs it, right?

    noseIf you live with chronic sinus infections or inflammation, sinusitis, you’ve likely tried many treatments or therapies to get relief. Sometimes, the only option is surgery though and this is proving to be quite a boon for many people who need it. In fact, according to a new study, over 3/4 of patients who needed endoscopic sinus surgery had good results.

    Endoscopic surgery involves using very small instruments that reach into the sinuses, allowing surgeons to operate without having to make incisions. These types of surgeries are called minimally invasive surgeries.

    Chronic sinusitis or rhinosinusitis (CRS) is defined as a condition where symptoms persist for more than three months, despite medical treatment. Statistics show that it affects about 14% to 16% of the American population. According to the American Academy of Allergy, Asthma & Immunology, CRS is a problem that is the most common chronic illness seen in Americans.

    Symptoms of CRS include:

    • stuffy nose,
    • sinus pain and pressure
    • headache
    • sneezing

    On top of being uncomfortable, CRS can affect the bottom line economically. There is not only the amount of money spent on treatments and therapies, but lost work and productivity.

    People who live with CRS often have, believe it or not, more overall body pain than and less social contact than people who live with more serious health issues, such as heart failure, COPD (chronic obstructive pulmonary disease) or back pain.

    To understand how effective surgery can be on patients with CRS, researchers examined 302 patients and followed them for about 18 months after. The results of the study were published in the most recent issue of the journal Otolaryngology – Head and Neck Surgery.

    What the results showed was that a majority of the patients, between 72% and 76%, showed significant improvements in their quality of life after having the surgery.

    Of course, not all patients are candidates for surgery and not all patients can be helped with this type of surgery, but the results are promising for many, particularly patients who are suffering with CRS and who are trying to decide if they should go ahead and have the procedure done.

    ~~~

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    Post from: Blisstree

    Sinus Surgery Improves Quality of Life

  • UK Appealing for Brain Donors

    Talking about organ donation usually brings to mind donating your heart, kidneys, and other commonly discussed organs, but did you realize that by donating your brain, you could help advance research in many diseases, including Parkinson’s disease?

    brain_ncThe Parkinson’s Disease Society has put out an appeal for people to donate their brains after death for research purposes. Although all brains are helpful, younger people with Parkinson’s are particularly encouraged to donate, so researchers may learn more about how the disease may come on early, as it did with actor Michael J. Fox.

    The United Kingdom isn’t the only place that can use an increase in organ donations for research; other countries have the same problem of not having enough material with which to work.

    Unfortunately, it’s often difficult enough to convince people to donate organs to help others live, it seems to be even more difficult to convince them to donate for research.

    While it may seem odd to publish such an appeal, the Society said that it issued a similar one in early 2009 and they succeeded in gaining more than double the number of donors on the Parkinson’s Brain Donor Register.

    What do you think? Would you consider such a donation once you no longer need your brain?

    ~~~

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    Post from: Blisstree

    UK Appealing for Brain Donors

  • Acupuncture & Sex Drive in Breast Cancer

    Women who have had breast cancer may see themselves feeling more sensual and able to enjoy sex if they have acupuncture to treat some of the frustrating side effects of some cancer treatments, such as hot flashes and night sweats, say researchers.

    istock_acupunctureHormone therapy, used to treat some types of breast cancers, is often taken for up to five years after a woman has completed chemotherapy. However, the side effects are often more than simply annoying. They can have a significant impact on quality of life. Not being able to sleep well is the root of many problems at the best of times, but it can be much more difficult when you’re trying to win a battle against a potentially fatal disease.

    There are medications currently available to counter some of the side effects but they are not always effective. Seeing as acupuncture has already been found to reduce hot flashes in postmenopausal women, researchers from the Henry Ford Hospital looked into its effectiveness in this situation, comparing acupuncture with standard medications.

    The results, which were published in the most recent issue of the Journal of Oncology, found that

    “Acupuncture offers patients a safe, effective and durable treatment option for hot flashes, something that affects the majority of breast cancer survivors. Compared to drug therapy, acupuncture actually has benefits, as opposed to more side effects,” says study lead author Eleanor Walker, M.D., division director of breast services in the Department of Radiation Oncology at Henry Ford Hospital.

    Fifty women were randomly assigned to undergo acupuncture or take venlaxafine, a commonly used medication in this patient group. Both groups received treatment for 12 weeks, all the while keeping a journal/diary to record how many and how often they experienced hot flashes. They also took surveys about their overall health and mental health.

    Although both groups showed a 50 percent drop in hot flashes and depressive symptoms at first, but after two weeks, the women who received acupuncture continued to have a drop in hot flashes, which was not the case in the medication group.

    This shows that acupuncture could be a reasonable option for some women who are taking hormone therapy after breast cancer treatment.

    ~~~

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    Post from: Blisstree

    Acupuncture & Sex Drive in Breast Cancer

  • 10 Important Facts About Birth Defects

    When a woman is pregnant, in her mind, her baby will be perfect. But perfect isn’t always what we think it will be. Sometimes, our perfect baby is born with a problem, such as spina bifida (hole in the back) or missing a limb, or a heart defect.

    child

    Birth defects can sometimes be prevented and January is National Birth Defects Prevention Month. The goal of the month is to educate as many people as possible, not just mothers, about prevention of preventable birth defects.

    Taken from the National Birth Defects Prevention Network, here are 10 important facts you should know about birth defects:

    1

    Birth defects affect one out of ever 33 babies in the United States and is the cause of death in one of every five infant deaths.

    2

    bÈbÈ 1er ‚geFolic acid (folate) is a vitamin that all women of childbearing age, including teens, should be taking. Having too little folic acid is one of the contributing factors to spine deformities, like spina bifida. Since the spine forms within the first few weeks of pregnancy and many pregnancies are not planned, it is best to have a reserve of folic acid always in the body, rather than just when a woman plans on getting pregnant.

    3

    Not all birth defects are obvious or found while the baby is in the hospital. Many birth defects only become obvious as the child grows and develops.

    4

    precious little feetSome birth defects, such as Down’s syndrome or spina bifida, can be found before the baby is born if the mother has recommended prenatal testing, such as ultrasounds.

    5

    Birth defects are costly for society. According to the Birth Defects Prevention Network, “birth defects have accounted for over 139,000 hospital stays during a
    single year, resulting in $2.5 billion in hospital costs alone. Families and the government share the burden of these costs. Additional costs due to lost wages or
    occupational limitations can affect families as well”

    6

    Birth defects can be caused by genetic or unknown factors, but lifestyle choices also play a significant role. This includes smoking, using drugs, drinking alcohol, and other actions. Occupational dangers can also contribute to birth defects.

    7

    sleeping beautyPrevention may be possible. Depending on the defect, women may be able to prevent some from occurring, be it having adequate nutrition, including folic acid, to good prenatal care and lifestyle choices.

    8

    Infections may cause some defects, but infections may often be prevented. We all try to keep from getting infected with various viruses and illnesses and women who are pregnant even more so. By proper handwashing, avoiding certain tasks, such as cleaning out cat litter boxes while pregnant, and avoiding sick people as much as possible, it is possible to limit exposure to infections, keeping the baby safer.

    9

    Avoiding alcohol is the best way to reduce the risk of certain birth defects. Although a general motto in our society is “moderation in everything,” alcohol and pregnancy don’t go together. No-one knows for sure how much is too much when it comes to the baby’s developing brain and body – so why take the risk?

    10

    Mom is the baby’s protector while pregnant. Pregnant women may consider themselves as the gatekeeper to their child’s health. Of course, not all defects are preventable and this is important to keep in mind. But the healthier the mother, the better a lifestyle she chooses to live the better the child’s chances of being born happy and healthy.

    ~~~

    Images: PhotoXpress.com

    Post from: Blisstree

    10 Important Facts About Birth Defects

  • January is Glaucoma Awareness Month

    It’s January again – funny how that comes around every 12 months, isn’t it? And with January and a new year, we’re back to Glaucoma Awareness Month.

    It seems that one month isn’t enough to help raise awareness for such a devastating disease. Glaucoma, which is really a group of diseases, hits what people seem to fear most – losing their eyesight. Glaucoma is a silent disease, it has no symptoms in its early stages, nothing that can warn you that it’s going to happen to you. This is why awareness is so important, particularly if you fall into a high risk category.

    awareness_logo

    What is Glaucoma?

    Glaucoma is the leading cause of preventable blindness around the world. While it’s more common among seniors, even babies can develop it. According to Glaucoma.org,

    Over 3 million Americans, and nearly 70 million people worldwide, have glaucoma. Experts estimate that half of them don’t know they have it. Combined with our aging population, we can see an epidemic of blindness looming if we don’t raise awareness about the importance of regular eye examinations to preserve vision.

    The disease isn’t complicated – for some reason, depending on the type of glaucoma, fluid pressure builds up in the eye. As this pressure increases, it presses on the optic nerve, the nerve that connects the retina to the brain and sends images for your brain to interpret into sight.

    The most common type of glaucoma is called primary open-angle glaucoma, but there are other less common ones as well:

    Risks

    As with many diseases, some people are at higher risk of developing glaucoma than are others. However, if you aren’t in one of the high risk groups, this doesn’t mean you may not develop it.

    The high risk groups include:

    • African Americans over age 40.
    • everyone over age 60, especially Mexican Americans.
    • people with a family history of glaucoma.

    Other risks include:

    • being severely near-sighted, or myopic
    • having high pressure level in the eye
    • having an enlarged optic nerve
    • sustaining eye trauma or injury
    • having diabetes
    • having had previous eye surgery
    • having taken long-term steroids, even for medical purposes

    Prevention

    The best treatment is – you guessed it – prevention. So, how do you prevent a disease you don’t know you may have? You have regular eye examinations, whether you are at risk or not. Obviously, those who are at risk should have more frequent ones, as recommended by their eye care health professional.

    Testing for glaucoma is not painful, uncomfortable, long, or tedious. All it involves is two tests:

    Tonometry
    The tonometry test measures the inner pressure of the eye. Usually drops are used to numb the eye. Then the doctor or technician will use a special device that measures the eye’s pressure.
    Ophthalmoscopy
    Ophthalmoscopy is used to examine the inside of the eye, especially the optic nerve. In a darkened room, the doctor will magnify your eye by using an ophthalmoscope (an instrument with a small light on the end). This helps the doctor look at the shape and color of the optic nerve.

    If the tests cause suspicion, then more tests will be recommended.

    Don’t take chances with your sight. Not when this is a treatable illness.

    ~~~

    Image: Glaucoma.org

    Post from: Blisstree

    January is Glaucoma Awareness Month

  • Montana to Allow Physician-Assisted Suicide

    Montana is going to be the third state in the United States to allow for physician-assisted suicide, say news reports. Currently, both Oregon and Washington state allow for physician-assisted suicide for terminally ill patients.

    08D-9314-0A year ago, news was made when a state District Court judge ruled that the terminally ill people in Montana were protected by the state’s constitutional rights and should be allowed to get the medications they needed to die on their own terms.

    This ruling wasn’t argued against, but in order to have it clarified and at the highest levels, advocates for physician-assisted suicide brought the case before the state Supreme Court. On Thursday, December 31, 2009, although the Supreme Court did not comment on the state constitution guaranteeing the right to die by physician-assisted suicide, the Court did say,

    “we find nothing in Montana Supreme Court precedent or Montana statutes indicating that physician aid in dying is against public policy.”

    It is a given that this issue has not been closed, as opponents to physician-assisted suicide pledge to fight on to the Legislature.

    ~~~

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    Montana to Allow Physician-Assisted Suicide

  • TENS Not Recommended for Chronic Back Pain

    Anyone who has experienced chronic lower back pain knows that there are many treatments to try, but it may be difficult to find one that works for your specific problem.

    Human backTranscutaneous electric nerve stimulation (TENS) is technique that many doctors and physiotherapists have been using to treat pain, including lower back pain. It’s a painless procedure that uses electrical currents to try to interrupt the pain signals from reaching the brain.

    Electrodes from the TENS machine are placed around or on the painful area and the machine is then turned on. Electrical currents are sent through the electrodes and into the body tissue. The currents don’t cause any pain, but some people do feel a bit uncomfortable.

    Now, new guidelines, published at the end of December 2009 in the journal Neurology say that TENS is not suitable for treating chronic lower back pain – that is pain that has lasted three months or longer. The researchers caution that this is not pertinent to acute back pain, new pain.

    Many studies have looked at the effectiveness of TENS and lower back pain, and according to this article, the only pain that can definitively be helped by TENS is diabetic neuropathy, pain in the nerve endings that develops as a result of progressing diabetes.

    “The strongest evidence showed that there is no benefit for people using TENS for chronic low-back pain,” said guideline author Richard M. Dubinsky, MD, MPH, of Kansas University Medical Center in Kansas City and a Fellow of the American Academy of Neurology. “Doctors should use clinical judgment regarding TENS use for chronic low-back pain. People who are currently using TENS for their low-back pain should discuss these findings with their doctors.”

    Have you used TENS for pain management?

    ~~~

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    TENS Not Recommended for Chronic Back Pain

  • FDA Warns Against Nzu for Morning Sickness

    Health warning re Nzu, Traditional Remedy for Morning Sickness

    Press Release

    Internet-News_NC

    [Posted 12/31/2009] The Texas Department of State Health Services and FDA notified healthcare professionals and consumers, especially pregnant or breastfeeding women, to avoid consuming a product called “Nzu”, taken as a traditional remedy for morning sickness,because of the potential health risks from high levels of lead and arsenic, noted on laboratory analysis by Texas DSHS.

    Exposure to lead can result in a number of harmful effects, and a developing child is particularly at risk of effects on the brain and nervous system. Arsenic is a carcinogen, and excessive long-term exposure to it has been associated with a range of adverse health effects, including cancers of the urinary bladder, lung and skin. Nzu, which is sold at African specialty stores is also called Calabash clay, Calabar stone, Mabele, Argile and La Craie. It generally resembles balls of clay or mud and is usually sold in small plastic bags with a handwritten label identifying it as “Nzu” or “Salted Nzu.” Anyone who has been ingesting the product should contact their health care provider.

    Any adverse events that may be related to use should be reported to the FDA’s MedWatch Safety Information and Adverse Event Reporting Program online, by phone 1-800-332-1088, or by returning the postage-paid FDA form 3500 [which may be downloaded from the MedWatch “Download Forms” page] by mail [to address on the pre-addressed form] or fax [1-800-FDA-0178].

    ~~~

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    FDA Warns Against Nzu for Morning Sickness

  • 10 Common Health New Years Resolutions

    Do you make New Year’s resolutions? If you do, you’re among many, many others who do. Maybe the question should be: Do you KEEP your New Year’s resolutions? If yes, you’re among a very small group of people.

    iStock_womenGymResolutions often focus on health. For some reason, we think more about getting healthy as a year draws to a close than any other time of year, except possibly when it’s bathing suit shopping time. Have you ever made any of these common New Year’s resolutions?

    I will:

    1. lose X amount of pounds this year (or a generic, I will lose weight)
    2. eat a more balanced, healthier diet
    3. join a gym/attend exercise classes
    4. walk X amount of minutes per day
    5. use the stairs instead of escalators/elevators when possible
    6. hydrate myself by drinking more water
    7. make time for myself, to treat myself better
    8. see my doctor for a regular check up/follow-ups
    9. go to bed earlier to get more sleep
    10. quit smoking/drink less

    ~~~

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    Post from: Blisstree

    10 Common Health New Years Resolutions

  • Music Therapy Promising for Tinnitus

    Most of us have had some sort of noise in our ears from time to time. It could be a high pitched tone or buzzing – but some people experience this type of noise each and every moment of their day.

    According to the American Tinnitus Association, tinnitus affects 50 million people in the United States and 12 million of them experience sound so bothersome iStock_earthat it’s disabling. The BBC reports that around 1% to 3% of people in the United Kingdom also have tinnitus that is “significant enough to reduce their overall quality of life.”

    Tinnitus strikes any age group, any walk of life, but some lifestyles contribute a higher risk to developing it than others. Professions that involve loud sounds, even music, are among them. Famous musicians who have talked about their tinnitus include Metallica drummer Lars Ulrich, Al Di Meola, Liberty DeVitto, Pete Townsend, Eric Clapton, and Phil Collins (Metallica’s Lars Ulrich Lives with Tinnitus).

    Right now, there is no treatment for tinnitus and researchers are working to find what causes it. However, according to a new study, published in the most recent issue of Proceedings of the National Academy of Sciences, music may help some people with the problem.

    Thirty-nine patients with chronic tinnitus were divided into three groups. One group listened to modified music therapy, which involves their listening to their favorite music with certain notes removed. These notes matched the tones of the sounds they heard as a result of the tinnitus. The subjects in the other two groups either listened to  a dummy version of music therapy or received usual treatment.

    The subjects who listened to the modified or dummy music, listened for an average of 12 hours per week for the length of the study (one year). The results showed that those who listened to the modified music reported that they had a significant improvement, drop, in the ringing in their ears than those who listened to the dummy music.

    This was a small study and just a start, but if the results can be reproduced, this could be a boon to the many people who experience the annoying and sometimes debilitating problem.

    ~~~

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    Post from: Blisstree

    Music Therapy Promising for Tinnitus

  • High-Dose Flu Vaccine Approved for Seniors

    FDA Approves A High Dose Seasonal Influenza Vaccine Specifically Intended for People Ages 65 and Older

    Internet-News_NC
    Accelerated approval process used in vaccine approval

    Press Release

    The U.S. Food and Drug Administration approved Fluzone High-Dose, an inactivated influenza virus vaccine for people ages 65 years and older to prevent disease caused by influenza virus subtypes A and B.

    People in this age group are at highest risk for seasonal influenza complications, which may result in hospitalization and death. Annual vaccination remains the best protection from influenza, particularly for people 65 and older.

    Fluzone High-Dose was approved via the accelerated approval pathway. FDA’s accelerated approval pathway helps safe and effective medical products for serious or life-threatening diseases become available sooner. In clinical studies, Fluzone High-Dose demonstrated an enhanced immune response compared with Fluzone in individuals 65 and older.

    As part of the accelerated approval process, the manufacturer is required to conduct further studies to verify that the Fluzone High-Dose will decrease seasonal influenza disease after vaccination.

    “As people grow older, their immune systems typically become weaker,” said Karen Midthun, M.D., acting director of the FDA’s Center for Biologics Evaluation and Research. “This is the first influenza vaccine that uses a higher dose to induce a stronger immune response that is intended to better protect the elderly against seasonal influenza.”

    Fluzone High-Dose, manufactured by Sanofi Pasteur Inc., is formulated so that each 0.5 mL dose contains a total of 180 micrograms (mcg) of influenza virus hemagglutinin (HA) which is made up of 60 mcg of each of the three influenza virus strains.

    Other currently licensed seasonal influenza vaccines for adults are formulated to contain a total of 45 mcg of influenza virus hemagglutinin (15 mcg HA from each of the three influenza strains per dose). Sanofi Pasteur, also manufactures Fluzone, a seasonal vaccine for the United States approved for use in individuals ages 6 months and older.

    As expected, because of the higher HA content, non-serious adverse events were more frequent after vaccination with Fluzone High-Dose compared with Fluzone. Common adverse events experienced during clinical studies included pain, redness and swelling at the injection site and headache, muscle aches, fever and malaise. The rate of serious adverse events was comparable between Fluzone High-Dose and Fluzone.

    People with hypersensitivity to egg proteins or life-threatening reactions after previous administration of any influenza vaccine should not be vaccinated with Fluzone High-Dose.

    Fluzone High-Dose is administered as a single injection in the upper arm and is available in single dose pre-filled syringes without preservative.

    For more information

    FDA Web Page on Vaccines, Blood & Biologics
    http://www.fda.gov/BiologicsBloodVaccines/default.htm.

    #

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    High-Dose Flu Vaccine Approved for Seniors

  • Top 10 Medical Stories for the Decade

    It’s easy to remember the most recent stories or advances in health and medicine – but what about what else has happened since the hysteria of Y2K? Whether it’s Terri Shiavo in 2005 or the H1N1 virus in 2009, it’s impossible to list a “top 10″ list with everyone in agreement. However, the idea of the top 10 lists is to help us remember, to think about what’s happened, and maybe to continue making a difference. Here is a list of top 10 health stories that did get a lot of press:

    Internet-News_NC2000: The Human Genome Project. Scientists had been working on mapping out the genes of humans and finally, in June 2000, they were able to present their draft of the human genome.

    2001: Anthrax scare. According to CNN.com news people, the anthrax scare made it to the top 10 news stories of the year. Envelopes with anthrax, a powdery, white substance, were being mailed to various locations throughout the United States. People were becoming afraid to open mail and any hint of a white powder set off security concerns.

    2002: Hormone replacement therapy became the new no-no in health. Researchers had been studying the use of hormones in 16,000 healthy postmenopausal women. The study was ended prematurely (after five years, instead of eight) because of an increase in the risk of breast cancer, heart disease, strokes and blood clots among women who were taking both estrogen and progestin.

    2003: SARS (Sudden Acute Respiratory Syndrome) – In early 2003, SARS came on the scene very suddenly. The virus spread easily from person to person and had a death rate of almost 10%.

    2004: Although not technically a health story, the story of the year had to be one that happened within its last week: the tsunami that killed over 230,000 people in countries around the Indian Ocean. This truly was a disaster of immense proportions and still affects the people in those countries today.

    2005: Terri Schiavo. On March 31, Terri Schindler Shiavo, died after becoming a cause celebre for living wills and the right to die. Fifteen years before, Terri experienced a cardiac arrest, at the age of 26 years. For 15 years, she remained alive only because of her feeding tube that provided nourishment directly into her stomach. Her husband wanted to discontinue her feedings, saying this is what Terri would have wanted. Her parents fought to keep Terri alive. (Terri’s foundation)

    syringe2006: HPV Vaccine, Gardasil. The United States FDA approved the use of Gardasil, a vaccine that helps reduce the infection rate of some forms of human papillomavirus, the virus that causes genital warts. Two of these viruses are known to contribute to the development of cervical cancer.

    2007: Children’s Cough Medicine – another no-no. It was in 2007 that news hit the wires: cough medicines were not mean for children under the age of 2 years and should not be given to them, despite directions on the label. The FDA did say that if the child’s doctor recommended it, that was ok, but for parents not to routinely give their children this type of medication.

    2008: New CPR Guidelines: Out with the old number of compression combined with number of breaths. The idea of having to give breaths of air while doing chest compressions was changed when researchers found it was better just to give effective and rapid chest compressions. This allowed the blood to circulate and provide the brain with much needed fresh blood.

    2009: H1N1 Virus. The H1N1 virus, or so-called swine flu, took over the health news in 2009. Whether it was overblown hype or a true near-disaster, we may never know. If the world responded well and prevented massive infection and deaths, then it was a success. If the disease wasn’t as bad as originally felt, then maybe it was overblown. Whichever it is/was, it was definitely the news maker of 2009.

    ~~~

    Images: iStock.com and PhotoXpress.com

    Post from: Blisstree

    Top 10 Medical Stories for the Decade

  • Air Pollution and Pneumonnia in Seniors

    This shouldn’t come as too much of a surprise to people, but researchers have found that prolonged exposure to higher levels of the pollution, particularly car exhaust fumes and industrial air pollution,  can lead to pneumonia in seniors. This pneumonia may be severe enough to require admission to hospital.

    smokestacks #217Researchers from McMaster University in Ontario, Canada, studied 365 seniors from the city of Hamilton, Ontario area to see if there was a connection between pollution and pneumonia. Their study findings will be published in early January 2010 in the  American Journal of Respiratory and Critical Care Medicine.

    The researchers found that exposure for more than 12 months to higher levels of nitrogen dioxide and fine particulate matter of less than 2.5 micrometres more than doubled the risk of hospitalization for pneumonia in adults aged 65 and older.

    Nitrogen dioxide is reportedly the major contributor to smog and results from the burning of fossil fuels.

    Pneumonia is a great risk to young children, people with chronic illnesses or who have problems with their immune system, and the elderly. It is listed as one of the leading causes of death among the elderly.

    The connection between pollution and pneumonia is a serious one, not only as the population ages in the developed countries – many of which have had issues with pollution – but as developing countries begin burning more fossil fuels in an effort to advance themselves.

    Symptoms of pneumonia may include:

    • Fever
    • Cough
    • Shortness of breath
    • Sweating
    • Shaking chills
    • Chest pain that fluctuates with breathing (pleurisy)
    • Headache
    • Muscle pain
    • Fatigue
    • Ironically, people in high-risk groups such as older adults and people with chronic illnesses or weakened immune systems may have fewer or milder symptoms than less vulnerable people do. And instead of having the high fever that often characterizes pneumonia, older adults may even have a lower than normal temperature. (MayoClinic.com)

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    Post from: Blisstree

    Air Pollution and Pneumonnia in Seniors

  • Abdominal Surgery Higher Risk for Seniors

    Any type of surgery has its risks, even so-called minor surgeries. But some surgeries are riskier than others and even more so for certain groups of people.

    Seniors, those aged 65  years or older, often undergo surgery for various ailments that have either been neglected over time or have developed over the years. And, as chirurgthe population ages, more surgeries will be done in that age group. According to a study just published in the Archives of Surgery, every year, approximately two million seniors have abdominal surgery.

    Abdominal surgeries, any type of surgery that involves the abdomen, are particularly risky for seniors, say researcher from the University of Washington School of Medicine in Seattle, Washington. The researchers were looking at complication and death rates of 101,318 seniors who underwent common abdominal procedures such as cholecystectomies (gall bladder removal), hysterectomies (removal of the uterus) and colectomies (removal of part of the colon).

    Seniors often have multiple medical problems, which could add to surgery risk, and the researchers point out that the seniors may also have a lower ability to tolerate the stress of surgery and any complications that may result. For this reason, the researchers found a complication rate and death rate of:

    • 14.6% and 2.5% for patients from 65 to 69 years
    • 16.1% and 3.8% for patients from 70 to 74 years
    • 18.8% and 6% for patients from 75 to 79 years
    • 19.9% and 8.1% for patients from 80 to 84 years
    • 22.6%  and 12.6% for patients from 85 to 89 years
    • 22.7% and 16.7% for patients who were 90 years or older

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    Image: PhotoXpress.com

    Post from: Blisstree

    Abdominal Surgery Higher Risk for Seniors

  • Warning: Glass Ornaments & Baby’s Mouths

    We all know that babies and young children put just about anything they can in their mouth and that’s why most of us work so hard to baby-proof our homes to avoid tragedy. The holiday season is full of things that can harm little ones and it’s important to think of the things we may  not consider as dangerous.

    Christmas ballSMany years ago, when my “baby” sister was a baby, I was minding her while my parents were out. I must have been about 14 or 15 and she was about a year and a half old. We had a piano in our dining room, which was an extension of the living room, where my sister’s playpen was – just beside the Christmas tree. I remember I was practicing the piano while she played in her pen – or so I thought.

    At some point, I turned around and her mouth was dripping with blood. In her hand, she was holding a broken, red Christmas tree ball. A broken, red *glass* Christmas tree bulb, that she had been biting and chewing on.

    I remember panicking, having no idea what to do. I didn’t know how long she’d been munching on this glass bulb and if she’s swallowed any glass. All I knew was if anything happened to her, I’d be in big, big trouble.

    All these years later, this sister is now in her mid-thirties and I remember that incident as if it was yesterday. As far as I know, she suffered no ill effects from the Christmas tree ball incident, but I know I never forgot. My kids were never allowed unsupervised near the tree and I limited the use of the glass bulbs as much as I could. The ones we did have were gifts.

    It turns out that my sister’s and my experience isn’t unique. The results of a new study out of Boston and published in the most recent issue of Pediatric Emergency Care (Holiday Ornament-Related Injuries in Children), found that glass ornaments were one of the worst safety hazards of Christmas decorations. Children who were injured were about 2 years old (ranging from 1.17-3.3 years) and with more boys (44.7% were girls).

    After examining 76 cases found over a 13-year period, the study’s authors concluded:

    Holiday ornament-related injuries primarily involve foreign body ingestions and glass-related injuries. Over half of the injuries involved small light bulbs and ornaments made of glass placed at the level a toddler can reach.

    Broken down:

    • 56% of the children ingested ornaments or fragments of ornaments or light bulbs into the mouth – only one was not made of glass
    • 28% of those who ingested the glass or bulbs experienced bleeding of the mouth or gastrointestinal tract
    • 27% of the children sustained lacerations (cuts), most of whom needed surgery to repaire
    • 85% of the children needed tests, such as x-rays or scans
    • 23% of the time, a specialist had to be consulted, most often for advice or help in removing the object(s)
    • 3 children were checked for toxin exposure
    • 2 children experienced minor electrocution

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    Image: PhotoXpress.com

    Post from: Blisstree

    Warning: Glass Ornaments & Baby’s Mouths